Evidence map›Paper›PMID 37026505›Full record

ReviewMolecular medicine reports2023

Advances in the application of molecular diagnostic techniques for the detection of infectious disease pathogens (Review).

Qingqing Liu, Xiaojuan Jin, Jun Cheng, Huajun Zhou, Yingjie Zhang, Yuzhu Dai

Open access · hybridAbstract readReview
In one paragraph

Review in Molecular medicine reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 74 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
74citing papers in PubMed, 1 pooled it
16.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

74 citing papers in PubMed, 1 synthesis or guideline pooled it, 147 citations in OpenAlex.

  1. Pooled it
  2. Review
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  6. Review
  7. Article
  8. Review
  9. Review
  10. Review
  11. Review
  12. Review
  13. Prevalence of astrovirus-associated gastroenteritis among hospitalized pediatric patients in Asia: A systematic review and meta-analysis.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2026
    Review
  14. Review
  15. Article
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14 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Qingqing Liu *School of Laboratory Medicine, Bengbu Medical College, Bengbu, Anhui 233000, P.R. China.
Xiaojuan Jin *Department of Clinical Research, The 903rd Hospital of The People's Liberation Army, Hangzhou, Zhejiang 310013, P.R. China.
Jun ChengDepartment of Clinical Research, The 903rd Hospital of The People's Liberation Army, Hangzhou, Zhejiang 310013, P.R. China.
Huajun ZhouDepartment of Clinical Research, The 903rd Hospital of The People's Liberation Army, Hangzhou, Zhejiang 310013, P.R. China.
Yingjie ZhangSchool of Laboratory Medicine, Bengbu Medical College, Bengbu, Anhui 233000, P.R. China.
Yuzhu DaiDepartment of Clinical Research, The 903rd Hospital of The People's Liberation Army, Hangzhou, Zhejiang 310013, P.R. China.
117th Hospital of People's Liberation Army · CNBengbu Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Infectious diseases are a major global cause of morbidity and mortality, seriously affecting public health and socioeconomic stability. Since infectious diseases can be caused by a wide variety of pathogens with similar clinical manifestations and symptoms that are difficult to accurately distinguish, selecting the appropriate diagnostic techniques for the rapid identification of pathogens is crucial for clinical disease diagnosis and public health management. However, traditional diagnostic techniques have low detection rates, long detection times and limited automation, which means that they do not meet the requirements for rapid diagnosis. Recent years have seen continuous developments in molecular detection technology, which has a higher sensitivity and specificity, shorter detection time and increased automation, and performs an important role in the early and rapid detection of infectious disease pathogens. The present study summarizes recent progress in molecular diagnostic technologies such as PCR, isothermal amplification, gene chips and high‑throughput sequencing for the detection of infectious disease pathogens, and compares the technical principles, advantages and disadvantages, applicability and costs of these diagnostic techniques.

Indexed as

Communicable DiseasesMolecular Diagnostic TechniquesHumansNucleic Acid Amplification TechniquesPolymerase Chain ReactionSensitivity and Specificitygene chiphigh‑throughput sequencinginfectious diseasesisothermal amplificationmolecular diagnostic techniquesPCR

Identifiers

PMID37026505
PMCPMC10086565
OpenAlexW4362590285

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.