Evidence map›Paper›PMID 37026487›Full record

ArticlePediatric blood & cancer2023

Neurocognitive and emotional factors predict pain-related healthcare utilization in children with sickle cell disease.

Steven J Hardy, Zaria Williams, Carly Berger, Danielle Griffin, Hannah Weisman, Hua Liang, Deepika S Darbari

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pediatric blood & cancer, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Steven J HardyDivision of Hematology, Children's National Hospital, Washington, District of Columbia, USA.ORCID 0000-0002-0491-4980
Zaria WilliamsHoward University College of Medicine, Washington, District of Columbia, USA.
Carly BergerDivision of Hematology, Children's National Hospital, Washington, District of Columbia, USA.
Danielle GriffinDivision of Hematology, Children's National Hospital, Washington, District of Columbia, USA.
Hannah WeismanDivision of Hematology, Children's National Hospital, Washington, District of Columbia, USA.
Hua LiangDepartment of Statistics, George Washington University, Washington, District of Columbia, USA.
Deepika S DarbariDivision of Hematology, Children's National Hospital, Washington, District of Columbia, USA.ORCID 0000-0002-0698-2936
Children's National · USGeorge Washington University · USHoward University · US

Funding

Clinical and Translational Science Institute at Children's NationalUL1TR000075 · NCATS · CHILDREN'S RESEARCH INSTITUTE · PI GUAY-WOODFORD, LISA MARIE · 2012 to 2015
$13.7M
Trajectory of Cognitive Functioning in Youth with Sickle Cell Disease without Cerebral InfarctionK23HL141666 · NHLBI · CHILDREN'S RESEARCH INSTITUTE · PI HARDY, STEVEN JAMES · 2019 to 2023
$698k
NCATS NIH HHS UL1 TR000075NHLBI NIH HHS K23 HL141666
6 · The paper itself

Abstract

backgroundYouth with sickle cell disease (SCD) experience increased rates of neurocognitive and emotional difficulties. Cross-sectional studies suggest neurocognitive and emotional functioning are associated with health outcomes in SCD. We investigated whether neurocognitive and emotional factors predicted future pain-related healthcare utilization in children with SCD. PROCEDURE: Total 112 youth with SCD between ages 7 and 16 years reported sociodemographics and completed measures of neurocognitive functioning and emotional well-being. The number of emergency department (ED) visits and hospitalizations for pain 1 and 3 years after enrollment were determined by chart review.

resultsThe mean age of participants was 10.61 years (standard deviation = 2.91), with most being female (n = 65; 58%). Eighty-three (74%) participants had either HbSS or HbSβ

conclusionsNeurocognitive and emotional factors are associated with subsequent healthcare use in youth with SCD. Poor attentional control might limit implementation of strategies to distract from pain or could make disease self-management behaviors more challenging. Results also highlight the potential impact of stress on pain onset, perception, and management. Clinicians should consider neurocognitive and emotional factors when developing strategies to optimize pain-related outcomes in SCD.

Indexed as

Anemia, Sickle CellQuality of LifeAdolescentChildCross-Sectional StudiesDelivery of Health CareFemaleHumansMalePainPatient Acceptance of Health Careattentioncognitiveemergency departmenthospitalizationpediatricquality of life

Identifiers

PMID37026487
PMCPMC13460263
OpenAlexW4362692192

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.