Evidence map›Paper›PMID 37026450›Full record

ArticleJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism2023

The GHB analogue HOCPCA improves deficits in cognition and sensorimotor function after MCAO via CaMKIIα.

Nane Griem-Krey, Anders B Klein, Bettina H Clausen, Mathias Rj Namini, Pernille V Nielsen, Mozammel Bhuiyan, Raghavendra Y Nagaraja, T Michael De Silva, Christopher G Sobey, Heung-Chin Cheng and 5 more

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 6 institutions in 4 countries.

Nane Griem-KreyDepartment of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark.
Anders B KleinDepartment of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0002-0236-3089
Bettina H ClausenDepartment of Neurobiology Research, Institute of Molecular Medicine, University of Southern Denmark, Odense, Denmark.
Mathias Rj NaminiDepartment of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0003-3399-207X
Pernille V NielsenDepartment of Neurobiology Research, Institute of Molecular Medicine, University of Southern Denmark, Odense, Denmark.
Mozammel BhuiyanDepartment of Anatomy, Brain Health Research Centre and Brain Research New Zealand, University of Otago, Dunedin, New Zealand.ORCID 0000-0002-5295-6456
Raghavendra Y NagarajaDepartment of Anatomy, Brain Health Research Centre and Brain Research New Zealand, University of Otago, Dunedin, New Zealand.
T Michael De SilvaDepartment of Microbiology, Anatomy, Physiology & Pharmacology and Centre for Cardiovascular Biology and Disease Research, School of Agriculture, Biomedicine & Environment, La Trobe University, Bundoora, Australia.
Christopher G SobeyDepartment of Microbiology, Anatomy, Physiology & Pharmacology and Centre for Cardiovascular Biology and Disease Research, School of Agriculture, Biomedicine & Environment, La Trobe University, Bundoora, Australia.ORCID 0000-0001-6525-9097
Heung-Chin ChengDepartment of Biochemistry and Pharmacology, University of Melbourne, Parkville, Australia.ORCID 0000-0002-4965-7148
Cyrille OrsetPhysiopathology and Imaging of Neurological Disorders, University of Caen Normandy, Caen, France.
Denis VivienPhysiopathology and Imaging of Neurological Disorders, University of Caen Normandy, Caen, France.
Kate L LambertsenDepartment of Neurobiology Research, Institute of Molecular Medicine, University of Southern Denmark, Odense, Denmark.ORCID 0000-0001-9276-4902
Andrew N ClarksonDepartment of Anatomy, Brain Health Research Centre and Brain Research New Zealand, University of Otago, Dunedin, New Zealand.
Petrine WellendorphDepartment of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0002-5455-8013
University of Copenhagen · DKLa Trobe University · AUUniversity of Southern Denmark · DKBrain Research New Zealand · NZPhysiopathologie et imagerie des troubles neurologiquesThe University of Melbourne · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ca

Indexed as

Sodium OxybateStrokeAnimalsCalcium-Calmodulin-Dependent Protein Kinase Type 2Carboxylic AcidsCognitionCyclopentanesMice3-hydroxycyclopent-1-enecarboxylic acidCalcium-Calmodulin-Dependent Protein Kinase Type 2Carboxylic AcidsCyclopentanesSodium OxybateCaMKIIexcitotoxicityfunctional recoveryHOCPCAMCAO

Identifiers

PMID37026450
PMCPMC10369146
OpenAlexW4362692017

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.