Evidence map›Paper›PMID 37026267›Full record

GuidelineIndian journal of ophthalmology2023

Autologous serum eye drops in dry eye disease: Preferred practice pattern guidelines.

Jayesh Vazirani, Uma Sridhar, Nikhil Gokhale, Venkateswara Rao Doddigarla, Savitri Sharma, Sayan Basu

Abstract readPractice GuidelineReview
In one paragraph

Guideline in Indian journal of ophthalmology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. The efficacy of autologous serum in corneal healing following metallic foreign body injuries.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2025
    Trial
  2. Article
  3. Long-Term Home Storage of Autologous Serum Eye Drops.Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie · 2026
    Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Blood Derivatives in the Therapy of Ocular Surface Diseases.International journal of molecular sciences · 2025
    Review
  9. Article
  10. Review
  11. Review
  12. Article
  13. Review
  14. Autologous blood in the management of ocular surface disorders.World journal of experimental medicine · 2024
    Review
  15. Review
  16. Review
  17. Review
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jayesh VaziraniCenter for Excellence in Cornea and Ocular Surface Disorders, Excel Eye Care, Ahmedabad, Gujarat, India.
Uma SridharDepartment of Cornea and Cataract, ICARE Eye Hospital and Postgraduate Institute, Noida, Uttar Pradesh, India.
Nikhil GokhaleCornea and Ocular Surface, Gokhale Eye Hospital, Mumbai, Maharashtra, India.
Venkateswara Rao DoddigarlaJhaveri Microbiology Centre, L V Prasad Eye Institute, Hyderabad, Telangana, India.
Savitri SharmaJhaveri Microbiology Centre, L V Prasad Eye Institute, Hyderabad, Telangana, India.
Sayan BasuThe Cornea Institute, Kallam Anji Reddy Campus, LV Prasad Eye Institute, Hyderabad, Telangana, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Autologous serum eye drops provide lubrication and promote epithelial healing. They have been successfully used in the management of ocular surface disorders such as dry eye disease, persistent epithelial defects and neurotrophic keratopathy for many decades. A great deal of variation in the methods of preparation of autologous serum eye drops, the end concentration and the duration of use exists in published literature. In this review, simplified recommendations for preparation, transport, storage and use of autologous serum are described. Evidence for the use of this modality in aqueous deficient dry eye disease is summarized, along with expertise-based rationale.

Indexed as

Corneal Dystrophies, HereditaryDry Eye SyndromesKeratitisHumansOphthalmic SolutionsSerumOphthalmic SolutionsAutologous serumdry eyeocular surface diseasepersistent epithelial defect

Identifiers

PMID37026267
PMCPMC10276663

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.