Evidence map›Paper›PMID 37026111›Full record

ArticleCureus2023

Blastic Plasmacytoid Dendritic Cell Neoplasm: A Case Report.

Abdulrahman Nasiri, Arwa Lami, Alanoud Alhumaidi, Afnan Madkhali, Amnah Althaqib, Norah Aljarwan, Reem Alkharras

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Cureus, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Abdulrahman NasiriHematology, King Faisal Specialist Hospital & Research Centre, Riyadh, SAU.
Arwa LamiInternal Medicine, Security Forces Hospital, Riydah, SAU.
Alanoud AlhumaidiInternal Medicine, Security Forces Hospital, Riyadh, SAU.
Afnan MadkhaliInternal Medicine, Security Forces Hospital, Riyadh, SAU.
Amnah AlthaqibInternal Medicine, Security Forces Hospital, Riyadh, SAU.
Norah AljarwanInternal Medicine, Security Forces Hospital, Riyadh, SAU.
Reem AlkharrasInternal Medicine, Security Forces Hospital, Riyadh, SAU.
King Faisal Specialist Hospital & Research Centre · SASecurity Forces Hospital · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is an uncommon hematological tumor originating from the precursor of plasmacytoid dendritic cells (pDCs) with a persistent and progressive course of illness. Despite being an aggressive disease BPDCN has an initial indolent course manifested as skin lesions. Alongside or following the skin lesion, the extra-cutaneous manifestation develops and includes lymphadenopathy, splenomegaly, and hepatomegaly. The BPDCN diagnosis is mainly based on the immunophenotype.  Herein, we report the case of a 72-year-old male patient who presented with a history of left anterior chest wall painless skin lesions. Histology of skin biopsy of the left chest skin lesion showed diffuse dermal infiltration by monomorphic medium-sized blastic cells positive for cluster of differentiation (CD)4, CD45, CD7, CD56, CD43, CD123, T-cell leukemia-1 (TCL1), and B-cell leukemia/lymphoma 2 protein (BCL2). Given the rarity of the disease, standard chemotherapy regimens used in treating different leukemias and lymphomas have been adapted to treat BPDCN.

Indexed as

azacytidinebcl-2blasticbpdcncd123dendriticneoplasmplasmacytoidrarevenetoclax

Identifiers

PMID37026111
PMCPMC10072177
OpenAlexW4362456671

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.