Evidence map›Paper›PMID 37025570›Full record

ArticleEuropean journal of breast health2023

Prognostic Factors Influencing Progression-Free Survival in HER2-Positive Metastatic Breast Cancer Patients Who Were Treated With A Combination of Lapatinib and Capecitabine.

İzzet Doğan, Nail Paksoy, Naziye Ak, Sezai Vatansever, Pınar Saip, Adnan Aydıner

Open access · diamondAbstract read
In one paragraph

Article in European journal of breast health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

İzzet DoğanDepartment of Medical Oncology, İstanbul University Institute of Oncology, İstanbul, Turkey.ORCID https://orcid.org/0000-0003-1018-1119
Nail PaksoyDepartment of Medical Oncology, İstanbul University Institute of Oncology, İstanbul, Turkey.ORCID https://orcid.org/0000-0003-4636-2595
Naziye AkDepartment of Medical Oncology, İstanbul University Institute of Oncology, İstanbul, Turkey.ORCID https://orcid.org/0000-0003-4636-2595
Sezai VatanseverDepartment of Medical Oncology, İstanbul University Institute of Oncology, İstanbul, Turkey.ORCID https://orcid.org/0000-0002-3108-0686
Pınar SaipDepartment of Medical Oncology, İstanbul University Institute of Oncology, İstanbul, Turkey.ORCID https://orcid.org/0000-0002-3108-0686
Adnan AydınerDepartment of Medical Oncology, İstanbul University Institute of Oncology, İstanbul, Turkey.ORCID https://orcid.org/0000-0002-1104-5840
Istanbul University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: The aim was to assess the prognostic variables in human epidermal growth factor receptor 2 (HER2)-positive metastatic breast cancer patients receiving lapatinib plus capecitabine. Materials and Methods: Retrospective data on HER2-positive metastatic breast cancer patients who received lapatinib and capecitabine were analyzed. Survival outcome was obtained with Cox regression analysis and the Kaplan-Meier method. Results: The study included 102 patients. Forty-four (43.1%) patients had Conclusion: These results have demonstrated the effectiveness of lapatinib plus capecitabine in metastatic HER2-positive breast cancer patients. Furthermore, unfavorable prognostic factors for progression-free survival were shown to be hormone-negative tumor,

Indexed as

Breast cancercapecitabineHER2/neu receptorlapatinibmetastasis

Identifiers

PMID37025570
PMCPMC10071882
OpenAlexW4362586374

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.