Evidence map›Paper›PMID 37025426›Full record

ArticleOpen medicine (Warsaw, Poland)2023

Efficacy of bronchoscopic intratumoral injection of endostar and cisplatin in lung squamous cell carcinoma patients underwent conventional chemoradiotherapy.

Yanzhen Ji, Shuli Luan, Xiaoping Yang, Bin Yin, Xiaojie Jin, Haiyan Wang, Wenqing Jiang

Open access · goldAbstract read
In one paragraph

Article in Open medicine (Warsaw, Poland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.8field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Yanzhen JiOtorhinolaryngological Department, Hiser Medical Center of Qingdao, Qingdao 266033, Shandong, China.
Shuli LuanDepartment of Geriatrics, Hiser Medical Center of Qingdao, Qingdao 266033, Shandong, China.
Xiaoping YangPneumology Department, Hiser Medical Center of Qingdao, Qingdao 266033, Shandong, China.
Bin YinPneumology Department, Hiser Medical Center of Qingdao, Qingdao 266033, Shandong, China.
Xiaojie JinPneumology Department, Hiser Medical Center of Qingdao, Qingdao 266033, Shandong, China.
Haiyan WangPneumology Department, Hiser Medical Center of Qingdao, Qingdao 266033, Shandong, China.
Wenqing JiangPneumology Department, Hiser Medical Center of Qingdao, No. 4 Renmin Road, Qingdao 266033, Shandong, China.
Qingdao Center of Resource Chemistry and New Materials · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bronchoscopy has been widely used for the therapy of lung cancer. This study aimed to evaluate the therapeutic efficacy and adverse reactions of bronchoscopic intratumoral injection of endostar and cisplatin in patients with lung squamous cell carcinoma (LSCC). A total of 40 LSCC patients who underwent conventional chemoradiotherapy were included in this study, and 20 of them received a bronchoscopic injection of endostar and cisplatin as an additive therapeutic modality (treatment group). The clinical response rate, progression-free survival (PFS), and adverse reactions of the patients were compared and analyzed. The treatment group had better short- and long-term therapeutic efficacy compared to the control group, but no significant differences were observed between the two therapeutic regimens in adverse reactions. Elderly and advanced LSCC patients had worse therapeutic efficacy and a high probability of adverse reactions after the therapy. Collectively, our analysis data demonstrated that the bronchoscopic intratumoral injection of endostar and cisplatin had improved therapeutic efficacy, and the cardiovascular adverse reactions were within the controllable range in the treatment of LSCC in clinical practices.

Indexed as

adverse reactionsbronchoscopycisplatinefficacyendostarlung squamous cell carcinoma

Identifiers

PMID37025426
PMCPMC10071812
OpenAlexW4362502051

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.