Evidence map›Paper›PMID 37025409›Full record

ArticleFrontiers in endocrinology2023

Incorporation size of lymph node metastasis focus and pre-ablation stimulated Tg could more effectively predict clinical outcomes in differentiated thyroid cancer patients without distant metastases.

Jiahao Xie, Pan Chen, Jing Wang, Xiaoqin Luo, Jiaxin Luo, Xiaoli Xiong, Chunyan Li, Liqin Pan, Juqing Wu, Huijuan Feng and 1 more

Erratum issuedAbstract read
In one paragraph

Article in Frontiers in endocrinology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
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  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Jiahao XieDepartment of Nuclear Medicine, The Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong, China.
Pan ChenDepartment of Nuclear Medicine, The Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong, China.
Jing WangDepartment of Nuclear Medicine, The Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong, China.
Xiaoqin LuoDepartment of Nuclear Medicine, The Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong, China.
Jiaxin LuoDepartment of Nuclear Medicine, The Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong, China.
Xiaoli XiongDepartment of Nuclear Medicine, The Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong, China.
Chunyan LiDepartment of Nuclear Medicine, The Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong, China.
Liqin PanDepartment of Nuclear Medicine, The Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong, China.
Juqing WuDepartment of Nuclear Medicine, The Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong, China.
Huijuan FengDepartment of Nuclear Medicine, The Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong, China.
Wei OuyangDepartment of Nuclear Medicine, The Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The size of lymph node metastasis (LNM) and pre-ablation stimulated Tg (ps-Tg) were key predictors of clinical prognosis in differentiated thyroid cancer (DTC) patients, however, very few studies combine the above two as predictors of clinical prognosis of DTC patients. Methods: Persistent/recurrent disease and clinicopathologic factors were analyzed in 543 DTC patients without distant metastases who underwent LN dissection, near-total/total thyroidectomy, and radioiodine ablation. Results: In the multivariate analysis, size of LNM, ps-Tg, and the activity of Conclusion: The cutoff of 0.4 cm and 1.4 cm for a definition of size of LNM in DTC patients without distant metastases can reclassify risk assessment, and incorporating ps-Tg could more effectively predict clinical outcomes and modify the postoperative management plan.

Indexed as

AdenocarcinomaThyroid NeoplasmsHumansIodine RadioisotopesLymphatic MetastasisThyroglobulinThyroidectomyIodine RadioisotopesThyroglobulin131I therapydifferentiated thyroid cancerlymph node metastasispre-ablation stimulated Tgprognosis

Identifiers

PMID37025409
PMCPMC10072321

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.