Non Invasive Ventilation's Effectiveness (NIV) in Patients with Interstitial Lung Disease and Hypercapnic Respiratory Failure.

Forogh Soltaninejad, Abbas Samim, Mehrzad Salmasi, Christoph Schőbel, Thomas Penzel, Awat Feizi, Babak Amra

Open access · greenAbstract read

In one paragraph

Article in Tanaffos, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact, top 69% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Forogh SoltaninejadBamdad Respiratory and Sleep Research Center, Department of Internal Medicine, Pulmonary Ward, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.

Abbas SamimDepartment of Internal Medicine, Pulmonary Ward, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.

Mehrzad SalmasiDepartment of Internal Medicine, Pulmonary Ward, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.

Christoph SchőbelUniversity of Duisburg-Essen, Center for Sleep Medicine, Ruhrland Hospital, University Hospital Essen, 45239, Essen, Germany.

Thomas PenzelCenter of Sleep Medicine, Charite - Universitatsmedizin Berlin, Berlin, Germany.

Awat FeiziDepartment of Biostatistics and Epidemiology, School of Health, Isfahan University of Medical Sciences, Isfahan, Iran.

Babak AmraBamdad Respiratory and Sleep Research Center, Department of Internal Medicine, Pulmonary Ward, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.

Isfahan University of Medical Sciences · IRUniversity of Duisburg-Essen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The therapeutic options for patients with interstitial lung disease (ILD) are limited. On the other hand, the role of noninvasive ventilation (NIV) in ILD management is not clear. This study investigated the effect of nighttime NIV in hypercapnic ILD patients. Materials and Methods: In this unblinded randomized clinical trial, we included a total of 20 ILD patients admitted in a specialized center with hypoxia, PaCO Results: The mean age of 20 patients enrolled was 62.57±6.67 and 40% were male. Although, a clinical significant improvement of dyspnea was detected in NIV group (P=0.046) after intervention, it was not statistically different from control group. Significant improvement was observed in physical functioning (P<0.001), social functioning (P=0.004) and pain (P=0.003) detected after 30 days in NIV group and the observed improvement in QoL was significantly higher than control group for physical functioning (P=0.042) and general health (0.049). Conclusion: Our results suggest NIV treatment in patients with ILD and hypercapnic respiratory failure could be advised in order to improve physical functioning.

Indexed as

HypercapniaInterstitial lung diseaseNoninvasive ventilationRespiratory insufficiencySurveys and questionnaires

Identifiers

PMID37025324

PMCPMC10073952

OpenAlexW4362692963

What OpenQuestion holds

Textmetadata

LicenceCC BY-NC

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.