ArticleFrontiers in pediatrics2023
Lung aeration reduces blood pressure surges caused by umbilical cord milking in preterm lambs.
Article in Frontiers in pediatrics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed, 4 citations in OpenAlex.
- Resuscitation With Placental Circulation Intact Compared With Cord Milking: A Randomized Clinical Trial.JAMA network open · 2024Trial
- Two-Year Outcomes of Umbilical Cord Milking in Nonvigorous Infants: A Secondary Analysis of the MINVI Randomized Clinical Trial.JAMA network open · 2024Trial
- Impact of resuscitation with 100% oxygen during physiological-based cord clamping or immediate cord clamping on lung inflammation and injury.Pediatric research · 2026Article
Corrections and comments
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Authors and funding
9 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Umbilical cord milking (UCM) at birth causes surges in arterial blood pressure and blood flow to the brain, which may explain the high risk of intraventricular haemorrhage (IVH) in extremely preterm infants receiving UCM. This high risk of IVH has not been reported in older infants. Objective: We hypothesized that lung aeration before UCM, reduces the surge in blood pressure and blood flow induced by UCM. Methods: At 126 days' gestation, fetal lambs ( Results: Both umbilical cord occlusions and UCM caused significant increases in carotid arterial blood flow and pressure. However, the increases in systolic and mean arterial blood pressure (10 ± 3 mmHg vs. 3 ± 2 mmHg, Conclusions: UCM after ventilation onset significantly reduces the increases in carotid blood flow and blood pressure caused by UCM.
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Registered trials
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