Evidence map›Paper›PMID 37025249›Full record

ArticleSAGE open medical case reports2023

Combined cemiplimab and radiotherapy for advanced basal cell carcinoma: A case report.

Sidra Sarfaraz, Robert C Hayes, Anne-Marie Hunt

Abstract readCase Reports
In one paragraph

Article in SAGE open medical case reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Sidra SarfarazFaculty of Medicine, Dalhousie University, Halifax, NS, Canada.ORCID https://orcid.org/0000-0001-5513-9753
Robert C HayesDivision of Clinical Dermatology & Cutaneous Science, Dalhousie Medicine New Brunswick, Saint John, NB, Canada.
Anne-Marie HuntDivision of Clinical Dermatology & Cutaneous Science, Dalhousie Medicine New Brunswick, Saint John, NB, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Advanced basal cell carcinoma may be treated with systemic therapies such as hedgehog pathway inhibitors or programmed cell death protein 1 inhibitors, namely cemiplimab. We report a case of a 70-year-old man with a nodulo-infiltrative advanced basal cell carcinoma over the right posterior neck and scapula. The patient had a partial response to the hedgehog pathway inhibitor, vismodegib. The tumour progressed, and the patient was switched from vismodegib to radiotherapy combined with cemiplimab, which led to a significant reduction in pain, bleeding, and tumour size. A combined treatment approach with radiotherapy and cemiplimab may be beneficial for advanced basal cell carcinoma cases that progress after treatment with hedgehog pathway inhibitors.

Indexed as

abscopal effectAdvanced basal cell carcinomacemiplimabradiotherapyvismodegib

Identifiers

PMID37025249
PMCPMC10071152

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.