Evidence map›Paper›PMID 37025067›Full record

ArticleCell proliferation2023

Spatially multicellular variability of intervertebral disc degeneration by comparative single-cell analysis.

Peng Lin, Pulin Yan, Jun Zhu, Sha Huang, Zhong Wang, Ou Hu, Huaijian Jin, Yangyang Li, Liang Zhang, Jianhua Zhao and 5 more

Open access · goldAbstract read
In one paragraph

Article in Cell proliferation, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 1 country.

Peng LinDepartment of Spine Surgery, Center of Orthopedics, State Key Laboratory of Trauma, Burns and Combined Injury, Daping Hospital, Army Medical University (Third Military Medical University), Chongqing, 400042, China.
Pulin YanDepartment of Spine Surgery, Center of Orthopedics, State Key Laboratory of Trauma, Burns and Combined Injury, Daping Hospital, Army Medical University (Third Military Medical University), Chongqing, 400042, China.
Jun ZhuDepartment of Spine Surgery, Center of Orthopedics, State Key Laboratory of Trauma, Burns and Combined Injury, Daping Hospital, Army Medical University (Third Military Medical University), Chongqing, 400042, China.
Sha HuangDepartment of Spine Surgery, Center of Orthopedics, State Key Laboratory of Trauma, Burns and Combined Injury, Daping Hospital, Army Medical University (Third Military Medical University), Chongqing, 400042, China.
Zhong WangDepartment of Spine Surgery, Center of Orthopedics, State Key Laboratory of Trauma, Burns and Combined Injury, Daping Hospital, Army Medical University (Third Military Medical University), Chongqing, 400042, China.
Ou HuDepartment of Spine Surgery, Center of Orthopedics, State Key Laboratory of Trauma, Burns and Combined Injury, Daping Hospital, Army Medical University (Third Military Medical University), Chongqing, 400042, China.
Huaijian JinDepartment of Spine Surgery, Center of Orthopedics, State Key Laboratory of Trauma, Burns and Combined Injury, Daping Hospital, Army Medical University (Third Military Medical University), Chongqing, 400042, China.
Yangyang LiDepartment of Spine Surgery, Center of Orthopedics, State Key Laboratory of Trauma, Burns and Combined Injury, Daping Hospital, Army Medical University (Third Military Medical University), Chongqing, 400042, China.
Liang ZhangDepartment of Spine Surgery, Center of Orthopedics, State Key Laboratory of Trauma, Burns and Combined Injury, Daping Hospital, Army Medical University (Third Military Medical University), Chongqing, 400042, China.
Jianhua ZhaoDepartment of Spine Surgery, Center of Orthopedics, State Key Laboratory of Trauma, Burns and Combined Injury, Daping Hospital, Army Medical University (Third Military Medical University), Chongqing, 400042, China.
Lin ChenCenter of Bone Metabolism and Repair, State Key Laboratory of Trauma, Burns and Combined Injury, Trauma Center, Research Institute of Surgery, Laboratory for the Prevention and Rehabilitation of Military Training Related Injuries, Daping Hospital, Army Medical University (Third Military Medical University), Chongqing, 400042, China.
Bing LiuState Key Laboratory of Proteomics, Academy of Military Medical Sciences, Academy of Military Sciences, Beijing, 100071, China.
Jian HeDepartment of Spine Surgery, Center of Orthopedics, State Key Laboratory of Trauma, Burns and Combined Injury, Daping Hospital, Army Medical University (Third Military Medical University), Chongqing, 400042, China.ORCID https://orcid.org/0000-0002-8632-4924
Yibo GanDepartment of Spine Surgery, Center of Orthopedics, State Key Laboratory of Trauma, Burns and Combined Injury, Daping Hospital, Army Medical University (Third Military Medical University), Chongqing, 400042, China.
Peng LiuDepartment of Spine Surgery, Center of Orthopedics, State Key Laboratory of Trauma, Burns and Combined Injury, Daping Hospital, Army Medical University (Third Military Medical University), Chongqing, 400042, China.ORCID https://orcid.org/0000-0002-6678-2266
Army Medical University · CNJinan University · CN

Funding

National Key Research and Development Program of China 2022YFA1103202National Natural Science Foundation of China 32200654National Natural Science Foundation of China 32270887National Natural Science Foundation of China 82272507Postdoctoral Innovative Talent Support Program 2019-298Postdoctoral Innovative Talent Support Program BX20220397The Open Project of State Key Laboratory of Trauma, Burns and Combined Injury SFLKF202201The Open Project of State Key Laboratory of Trauma, Burns and Combined Injury SKLYQ201902Training Plan of Talents' Innovation of Army Medical Center of PLA 2019CXJSB013
6 · The paper itself

Abstract

Previous studies have revealed cellular heterogeneity in intervertebral discs (IVDs). However, the cellular and molecular alteration patterns of cell populations during degenerative progression remain to be fully elucidated. To illustrate the cellular and molecular alteration of cell populations in intervertebral disc degeneration (IDD), we perform single cell RNA sequencing on cells from four anatomic sites of healthy and degenerative goat IVDs. EGLN3

Indexed as

Intervertebral DiscIntervertebral Disc DegenerationCell DifferentiationEndothelial CellsHumansReceptors, G-Protein-CoupledStem CellsGPRC5A protein, humanReceptors, G-Protein-Coupled

Identifiers

PMID37025067
PMCPMC10542621
OpenAlexW4362692125

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.