Evidence map›Paper›PMID 37024887›Full record

ArticleBMC ophthalmology2023

Bacillary layer detachment with malignant choroidal tumors: a case series.

Yousef Ahmed Fouad, Abdelrahman Gaber Salman, Doaa Maamoun Ashour, Mohamed Sabry Elkady, Noha Abdel-Khalek, Mohamed Nowara, Weam Mohamed Ebeid

Open access · goldAbstract read
In one paragraph

Article in BMC ophthalmology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Yousef Ahmed FouadOphthalmology Department, Ain Shams University, Ramses st, Cairo, 11517, Cairo, Egypt. yousef.a.fouad@gmail.com.
Abdelrahman Gaber SalmanOphthalmology Department, Ain Shams University, Ramses st, Cairo, 11517, Cairo, Egypt.
Doaa Maamoun AshourOphthalmology Department, Ain Shams University, Ramses st, Cairo, 11517, Cairo, Egypt.
Mohamed Sabry ElkadyClinical Oncology Department, Ain shams University, Cairo, Egypt.
Noha Abdel-KhalekOphthalmology Department, Ain Shams University, Ramses st, Cairo, 11517, Cairo, Egypt.
Mohamed NowaraVitreoretinal Service, Al Mashreq Eye Center, Cairo, Egypt.
Weam Mohamed EbeidOphthalmology Department, Ain Shams University, Ramses st, Cairo, 11517, Cairo, Egypt.
Ain Shams University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo study the incidence and characteristics of bacillary layer detachment (BALAD) occurring with the two most common choroidal malignancies, choroidal metastasis and choroidal melanoma.

methodsA retrospective multicentric record analysis. Eyes with a diagnosis of choroidal melanoma or choroidal metastasis that had good-quality fundus photography and spectral domain optical coherence tomography (OCT) scans of the macular and tumor regions allowing for delineation of the retinal layers were included for analysis. Qualitative image evaluation was done by two independent graders for the presence, location, and OCT features of BALAD, as well as any associated intraretinal or subretinal fluid. Demographic and clinical data were also retrieved.

resultsOf the 11 eyes with choroidal metastasis and 7 eyes with choroidal melanoma that were included in the final analysis, 6 (54.5%) and 1 (14.3%) had BALAD, respectively. The BALAD co-localized with the subretinal fluid in all cases and with the intraretinal fluid in 1/3 cases (33.3%), was foveal in location in 3 eyes (42.9%), was overlying the tumor in 6 eyes (85.7%), and varied in number and size. Reflectivity within the BALAD was consistently higher than the vitreous and adjacent subretinal fluid, and discernable suspended hyperreflective particles were noted in 5 eyes (71.4%).

conclusionBALAD is relatively common with choroidal metastasis. The OCT features described supplement our recognition of this new entity.

Indexed as

BacillusChoroid NeoplasmsMelanomaFluorescein AngiographyHumansRetinaRetrospective StudiesTomography, Optical CoherenceUveal MelanomaUveal NeoplasmsBacillary Layer detachmentBALADChoroidal MelanomaChoroidal MetastasisChoroidal tumors

Identifiers

PMID37024887
PMCPMC10077734
OpenAlexW4362668263

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.