ReviewBMC medical imaging2023
Sclerosing angiomatoid nodular transformation of the spleen: multimodality imaging features and literature review.
Review in BMC medical imaging, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Sclerosing angiomatoid nodular transformation of the spleen in an 18-year-old man: a case report.Journal of surgical case reports · 2026Article
- T2 hypointense lesions of the abdomen: imaging spectrum and diagnostic considerations.Abdominal radiology (New York) · 2026Review
- Characterization of CT and MRI findings in sclerosing angiomatoid nodular transformation of the spleen: novel discovery of peritumoral vascular signs.Quantitative imaging in medicine and surgery · 2025Article
- Sclerosing angiomatoid nodular transformation of the spleen: clinical, computed tomography, and magnetic resonance imaging characteristics.Quantitative imaging in medicine and surgery · 2025Article
- A case of sclerosing angiomatoid nodular transformation with central calcification.Radiology case reports · 2025Article
- Case Report: Sclerosing angiomatoid nodular transformation of the spleen: surgery or conservative treatment?Frontiers in immunology · 2025Article
- The Spectrum of Solitary Benign Splenic Lesions-Imaging Clues for a Noninvasive Diagnosis.Diagnostics (Basel, Switzerland) · 2023Review
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Authors and funding
4 authors.
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No grant is acknowledged in the PubMed record.
Abstract
objectiveThe purpose of this study was to evaluate the CT and MRI findings, clinicopathologic features, and differential diagnosis of Sclerosing angiomatoid nodular transformation (SANT). METHODS AND MATERIALS: Seven men and seven women with pathological diagnoses of SANT were included in this retrospect study. Patients underwent at least one radiological examination before surgery. The number, shape, margin, size, attenuation, signal intensity, homogeneity, and enhancing pattern of the lesion were evaluated by two abdominal radiologists independently. Immunohistochemistry reports were available for 11 patients. The immunoreactivity to the vascular markers CD8, CD31, and CD34 was assessed.
resultsThe 14 SANT patients (7 men, 7 women; mean age, 43.5 years; age range, 24-56 years) presented with a single lesion and showed no specific clinical symptoms. Among 14 patients, 12 patients underwent MR scan, 5 patients underwent CT scan and 3 patients underwent PET-CT. On CT, all 5 lesions showed hypodensity on non-contrast images and spoke-wheel enhancing pattern after contrast administration, and calcification was observed. On T2WI, 10 cases(83.3%)showed hypointensity and 2 cases (16.7%) showed hyperintensity with central hypointensity. On T1WI, 10 cases (83.3%) were isointense and 2 cases (16.7%) were slightly hypointense. 10 cases (83.3%) showed hypointensity on DWI and 2 cases (16.7%) showed slightly hyperintensity on DWI. After contrast administration, all 12 lesions showed progressive enhancement. 18 F-fluorodeoxyglucose (FDG) uptake in the tumor was seen in all three cases that underwent PET-CT. The maximum standardized uptake value (SUVmax) was 4.5, 5.1, and 3.8 respectively.
resultsApart from the progressive spoke-wheel enhancing pattern, DWI and ADC findings will add value to the diagnosis of SANT.
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