Evidence map›Paper›PMID 37024836›Full record

ArticleBMC ophthalmology2023

Phaco-goniosynechialysis versus phaco-trabeculectomy in patients with refractory primary angle-closure glaucoma: a comparative study.

Jiahui Zhao, Chenguang Zhang, Emmanuel Eric Pazo, Guangzheng Dai, Yunyan Li, Yimeng Chen, Mingze Li, Huixin Che

Registry-linked trialAbstract read
In one paragraph

Article in BMC ophthalmology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06952153 (Comparison of Phaco Surgery and Goniosynechialysis Versus Trabeculectomy Outcomes in Glaucoma Patients), which is not on this map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06952153 narecruitingnot on this mapstarted 2025, after this paper: background citation

Comparison of Phaco Surgery and Goniosynechialysis Versus Trabeculectomy Outcomes in Glaucoma Patients

TypeinterventionalSponsorUniversity of Medicine and Pharmacy at Ho Chi Minh CityRan2025 to 2027Enrolled82ConditionsPrimary Angle Closure GlaucomaArmsPhacoemulsification with Goniosynechialysis, Trabeculectomy with 5FU
3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jiahui ZhaoJinzhou Medical University, Linghe District, Jinzhou, 121004, China.
Chenguang ZhangHe Eye Specialist Hospital, No. 128 Huanghe North Street, Shenyang City, 110001, China.
Emmanuel Eric PazoHe Eye Specialist Hospital, No. 128 Huanghe North Street, Shenyang City, 110001, China.
Guangzheng DaiHe Eye Specialist Hospital, No. 128 Huanghe North Street, Shenyang City, 110001, China.
Yunyan LiHe Eye Specialist Hospital, No. 128 Huanghe North Street, Shenyang City, 110001, China.
Yimeng ChenJinzhou Medical University, Linghe District, Jinzhou, 121004, China.
Mingze LiHe Eye Specialist Hospital, No. 128 Huanghe North Street, Shenyang City, 110001, China.
Huixin CheHe Eye Specialist Hospital, No. 128 Huanghe North Street, Shenyang City, 110001, China. chehuixin@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo compare the effects of phacoemulsification with intraocular lens implantation (phaco) combined with goniosynechialysis (phaco + GSL) versus phaco with trabeculectomy (phaco + trab) for the management of primary angle-closure glaucoma (PACG) refractory to peripheral anterior synechiae (PAS) of over 180°.

methodsThis retrospective study followed 77 eyes of 77 patients for at least 6 months. Intraocular pressure (IOP), best-corrected visual acuity (BCVA), number of glaucoma drugs, and PAS were recorded at the preoperative baseline and evaluated at each postoperative follow-up visit. The National Eye Institute Visual Functioning Questionnaire-25 (NEI VFQ-25) was administered to patients enrolled in this study. Pearson's correlation analysis and multivariate linear analysis were performed to identify factors influencing changes in NEI VFQ-25 scores and to identify factors associated with increases in NEI VFQ-25 scores after the operation.

resultsIn total, seventy-seven eyes were included (43 with phaco + GSL and 34 with phaco + trab). Comparing preoperative baseline and month 6 after surgery measurements revealed that both groups found significant improvements in IOP, PAS, BCVA and the number of glaucoma drugs (P < 0.05). Baseline NEI VFQ-25 scores were similar in the two groups, but there was a significant difference in postoperative NEI VFQ-25 scores (74.47 ± 10.39 in phaco + GSL vs. 69.57 ± 8.54 in phaco + trab, P = 0.048 < 0.05), and the phaco + GSL group had better scores at the time of the last follow-up. The change in preoperative scores and the number of glaucoma drugs was significantly correlated with postoperative scores in the phaco + GSL group.

conclusionPhaco + GSL treatment is as safe and effective as phaco + trab for refractory PACG patients, and patients' subjective experience improved significantly after phaco + GSL surgery.

Indexed as

GlaucomaGlaucoma, Angle-ClosureIris DiseasesPhacoemulsificationTrabeculectomyEyeHumansIntraocular PressureRetrospective StudiesTreatment OutcomeGoniosynechialysisNEI VFQ-25Primary angle-closure glaucomaTrabeculectomy

Identifiers

PMID37024836
PMCPMC10080734

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.