ArticleNature microbiology2023
Vaccine plus microbicide effective in preventing vaginal SIV transmission in macaques.
Erratum issuedOpen access · hybridAbstract read
In one paragraph
Article in Nature microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 14 papers.
0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 10 citations in OpenAlex.
- Preferential engagement of the anti-inflammatory ATP/adenosine axis by HIV vaccine candidate with V1-deleted envelope in male rhesus macaques.Cell reports. Medicine · 2026Article
- Sustained mucosal delivery of SAMT-247 via an intravaginal ring reduces the risk of SIVCell reports. Medicine · 2026Article
- Global Proteomics Investigation of SAMT-247 Targets: An Antiviral Thioester that Acetylates Zinc Finger Proteins.bioRxiv : the preprint server for biology · 2026Article
- Friend or foe: divergent immunomodulatory effects of metabolites derived from the virucidal zinc finger inhibitor SAMT-247.Frontiers in immunology · 2026Article
- Sulfanylbenzamides with Unique Side Chains to Improve Metabolic Stability, Pharmacokinetics, and Anti-HIV Activity.Journal of medicinal chemistry · 2025Article
- HIV vaccine candidate ΔV1gp120 formulated in ALFQA adjuvant augments mucosal immunity in female macaques.Nature communications · 2025Article
- Online Conference "Chronic Viral Infections and Cancer, Openings for Vaccines and Cure" VIRCAN2024, Monitoring the Progress.Vaccines · 2025Article
- Development and optimization of human T-cell leukemia virus-specific antibody-dependent cell-mediated cytotoxicity (ADCC) assay directed to the envelope protein.Journal of virology · 2025Article
- Immunogenicity and protection mediated by dmLT and alum adjuvants for an HIV-1 vaccine.Frontiers in immunology · 2025Article
- Loss of HIV candidate vaccine efficacy in male macaques by mucosal nanoparticle immunization rescued by V2-specific response.Nature communications · 2024Article
- The quest for nanoparticle-powered vaccines in cancer immunotherapy.Journal of nanobiotechnology · 2024Review
- Vaccine induced mucosal and systemic memory NK/ILCs elicit decreased risk of SIV/SHIV acquisition.Frontiers in immunology · 2024Article
- Antibody-dependent cellular cytotoxicity, infected cell binding and neutralization by antibodies to the SIV envelope glycoprotein.PLoS pathogens · 2023Article
- Cholera toxin B scaffolded, focused SIV V2 epitope elicits antibodies that influence the risk of SIVFrontiers in immunology · 2023Article
Corrections and comments
- Erratum issued
Authors and funding
21 authors at 4 institutions in 1 country.
Mohammad Arif Rahman *Animal Models and Retroviral Vaccines Section, National Cancer Institute, Bethesda, MD, USA.ORCID http://orcid.org/0000-0002-6120-8943
Massimiliano Bissa *Animal Models and Retroviral Vaccines Section, National Cancer Institute, Bethesda, MD, USA.ORCID http://orcid.org/0000-0003-3455-3992
Isabela Silva de Castro *Animal Models and Retroviral Vaccines Section, National Cancer Institute, Bethesda, MD, USA.
Sabrina Helmold Hait *Section on Immune Biology of Retroviral Infection, National Cancer Institute, Bethesda, MD, USA.
James D StamosAnimal Models and Retroviral Vaccines Section, National Cancer Institute, Bethesda, MD, USA.
Farzana BhuyanTranslational Autoinflammatory Diseases Section, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
Ruth HunegnawSection on Immune Biology of Retroviral Infection, National Cancer Institute, Bethesda, MD, USA.
Sarkis SarkisAnimal Models and Retroviral Vaccines Section, National Cancer Institute, Bethesda, MD, USA.
Anna GutowskaAnimal Models and Retroviral Vaccines Section, National Cancer Institute, Bethesda, MD, USA.ORCID http://orcid.org/0000-0002-9873-6432
Melvin N DosterAnimal Models and Retroviral Vaccines Section, National Cancer Institute, Bethesda, MD, USA.
Ramona MolesAnimal Models and Retroviral Vaccines Section, National Cancer Institute, Bethesda, MD, USA.
Tanya HoangSection on Immune Biology of Retroviral Infection, National Cancer Institute, Bethesda, MD, USA.
Lisa M Miller JenkinsCollaborative Protein Technology Resource, Laboratory of Cell Biology, National Cancer Institute, Bethesda, MD, USA.ORCID http://orcid.org/0000-0003-1245-1338
Ettore AppellaChemical Immunology Section, National Cancer Institute, Bethesda, MD, USA.ORCID http://orcid.org/0000-0003-0569-9722
David J VenzonBiostatistics and Data Management Section, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA.ORCID http://orcid.org/0000-0002-8990-158X
Hyoyoung Choo-WosobaBiostatistics and Data Management Section, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA.
Timothy CardozoNew York University School of Medicine, NYU Langone Health, New York, NY, USA.ORCID http://orcid.org/0000-0002-0643-4497
Marc M BaumOak Crest Institute of Science, Monrovia, CA, USA.ORCID http://orcid.org/0000-0003-1558-5649
Daniel H AppellaSynthetic Bioactive Molecules Section, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, USA.
Marjorie Robert-GuroffSection on Immune Biology of Retroviral Infection, National Cancer Institute, Bethesda, MD, USA.
Genoveffa FranchiniAnimal Models and Retroviral Vaccines Section, National Cancer Institute, Bethesda, MD, USA. franchig@mail.nih.gov.ORCID http://orcid.org/0000-0003-2851-6589
National Cancer Institute · USNational Institutes of Health · USNew York University · USOak Crest Institute of Science · US
Funding
Preventive Vaccines for HIVZIABC011126 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI FRANCHINI, GENOVEFFA · 2009 to 2025
$55.3MOffice of Collaborative BiostatisticsZIDSC007202 · NCI · DIVISION OF CLINICAL SCIENCES - NCI · PI CHOO-WOSOBA, HYOYOUNG · 2009 to 2025
$14.5MCPTR - Mass Spectrometry UnitZICBC011430 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI JENKINS, LISA · 2012 to 2025
$9.4MResource for Nonhuman Primate Cell Depleting AntibodiesR24OD010976 · OD · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI ENGELMAN, KATHLEEN, MAGNANI, DIOGO · 2012 to 2019
$4.7MNIAID NIH HHS HHSN272201300031CNIH HHS R24 OD010976
Abstract
The human immunodeficiency virus epidemic continues in sub-Saharan Africa, and particularly affects adolescent girls and women who have limited access to antiretroviral therapy. Here we report that the risk of vaginal simian immunodeficiency virus (SIV)
Indexed as
Anti-Infective AgentsSAIDS VaccinesSimian Acquired Immunodeficiency SyndromeSimian Immunodeficiency VirusVaccinesAdolescentAnimalsFemaleHumansMacaca mulattaAnti-Infective AgentsSAIDS VaccinesVaccines
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.