ArticleCommunications biology2023
Chemical and genomic characterization of a potential probiotic treatment for stony coral tissue loss disease.
Article in Communications biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
37 citing papers in PubMed.
- Bacterial inoculation elicits changes to the coral epigenome.Nature communications · 2026Article
- Assessment of multiple probiotic strains that protectMicrobiology spectrum · 2026Article
- Symbiotic state affects microbiome recovery in a facultatively symbiotic cnidarian.Scientific reports · 2026Article
- Review
- Endozoicomonas acroporae enhances coral thermal resilience through host-microbe coordination.The ISME journal · 2026Article
- The Coral Host Microbiome Modulates the Virulence of the Bacterial Pathogen Vibrio coralliilyticus.Environmental microbiology · 2026Article
- Coral larvae have unique transcriptomic responses to pathogenic and probiotic bacteria.Coral reefs (Online) · 2026Article
- Evaluating stress antagonists for enhanced coral recovery after natural heat exposure.Scientific reports · 2025Article
- Near complete local extinction of iconic anemonefish and their anemone hosts following a heat stress event.npj biodiversity · 2025Article
- Heatwave-driven persistent microbes threaten the resilience of Mediterranean coral holobionts.Environmental microbiome · 2025Article
- Evaluating the effect of amoxicillin treatment on the microbiome ofApplied and environmental microbiology · 2025Article
- Bacterial Dynamics in Newly Settled Acropora kenti: Insights From Inoculations With Individual Probiotic Candidates.Environmental microbiology · 2025Article
- The Coral Probiotics Village: An Underwater Laboratory to Tackle the Coral Reefs Crisis.Ecology and evolution · 2025Article
- Phototrophic bacteria as potential probiotics for corals.npj biodiversity · 2025Review
- Article
- Discovery of Peptidic Siderophore Degradation by Screening Natural Product Profiles in Marine-Derived Bacterial Mono- and Cocultures.Biochemistry · 2025Article
- Halobacteriovorax halts disease progression in endangered Caribbean corals.The ISME journal · 2025Article
- Shifts in the microbiome and virome are associated with stony coral tissue loss disease (SCTLD).ISME communications · 2025Article
- Probiotics prevent mortality of thermal-sensitive corals exposed to short-term heat stress.ISME communications · 2025Article
- Tank-based bacterial profiling identifies basin-wide white band disease pathogen candidate and no bacterial associations with coral disease resistance.ISME communications · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors.
Funding
Abstract
Considered one of the most devastating coral disease outbreaks in history, stony coral tissue loss disease (SCTLD) is currently spreading throughout Florida's coral reefs and the greater Caribbean. SCTLD affects at least two dozen different coral species and has been implicated in extensive losses of coral cover. Here we show Pseudoalteromonas sp. strain McH1-7 has broad-spectrum antibacterial activity against SCTLD-associated bacterial isolates. Chemical analyses indicated McH1-7 produces at least two potential antibacterials, korormicin and tetrabromopyrrole, while genomic analysis identified the genes potentially encoding an L-amino acid oxidase and multiple antibacterial metalloproteases (pseudoalterins). During laboratory trials, McH1-7 arrested or slowed disease progression on 68.2% of diseased Montastraea cavernosa fragments treated (n = 22), and it prevented disease transmission by 100% (n = 12). McH1-7 is the most chemically characterized coral probiotic that is an effective prophylactic and direct treatment for the destructive SCTLD as well as a potential alternative to antibiotic use.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.