ArticlePLoS pathogens2023
Cell death as a defense strategy against pathogens in plants and animals.
Article in PLoS pathogens, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
8 citing papers in PubMed.
- Regulated cell death in fungi from a comparative immunology perspective.Cell death and differentiation · 2026Review
- The role of plant metacaspases in cell death and survival.Cell death and differentiation · 2026Review
- Navigating Transition Metal-Dependent Cell Death: Mechanisms, Crosstalk, and Future Directions.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Review
- Silicon Soil Amendment and Arbuscular Mycorrhizae Inoculation Enhance Eggplant Defense Against Rhizoctonia solani by Promoting Growth and Mitigating Root Rot Stress.Current microbiology · 2025Article
- Mitogen-Activated Protein Kinase Kinase OsMEK2 Positively Regulates CaAntioxidants (Basel, Switzerland) · 2024Article
- Apoptosis is mediated by FeHV-1 through the intrinsic pathway and interacts with the autophagic process.Virology journal · 2023Article
- Article
- Product safety aspects of plant molecular farming.Frontiers in bioengineering and biotechnology · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Eukaryotes are endowed with sophisticated innate immune systems to recognize non-self and halt pathogen proliferation. Activation of cell death at the site of attempted pathogen ingress is a common strategy used by plants and animals to restrict pathogen proliferation and trigger immune responses in the surrounding tissues. As such, immunogenic cell death shares several features in both plants and animals that will be discussed in this article, namely: (i) it is triggered by activation of NLR immune receptors-often through oligomerization; (ii) it results in disruption of the plasma membrane (PM)/endomembrane integrity driving an imbalance in ion fluxes; and (iii) it results in the release of signaling molecules from dying cells.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.