Evidence map›Paper›PMID 37022779›Full record

ReviewSchizophrenia bulletin2023

Review of Major Social Determinants of Health in Schizophrenia-Spectrum Psychotic Disorders: I. Clinical Outcomes.

Dylan J Jester, Michael L Thomas, Emily T Sturm, Philip D Harvey, Matcheri Keshavan, Beshaun J Davis, Shekhar Saxena, Rajesh Tampi, Heather Leutwyler, Michael T Compton and 2 more

Open access · greenAbstract readReview
In one paragraph

Review in Schizophrenia bulletin, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
67citing papers in PubMed, 7 pooled it
28.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

67 citing papers in PubMed, 7 syntheses or guidelines pooled it, 105 citations in OpenAlex.

  1. Pooled it
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  4. A meta-analysis of the role of neighborhood deprivation in psychotic disorders.Social psychiatry and psychiatric epidemiology · 2025
    Pooled it
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  8. Trial
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  15. Real-world comprehensive care of people living with schizophrenia: recommendations across different settings and clinical stages.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2026
    Article
  16. Article
  17. Review
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7 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 9 institutions in 1 country.

Dylan J JesterDepartment of Psychiatry, University of California, San Diego, CA, USA.
Michael L ThomasDepartment of Psychology, Colorado State University, Fort Collins, CO, USA.
Emily T SturmDepartment of Psychology, Colorado State University, Fort Collins, CO, USA.
Philip D HarveyDepartment of Psychiatry, University of Miami Miller School of Medicine, and Research Service, Bruce W. Carter Miami VA Medical Center, Miami, FL, USA.
Matcheri KeshavanDepartment of Psychiatry, Beth Israel Deaconess medical Center and Harvard Medical School, Boston, MA, USA.
Beshaun J DavisDepartment of Psychiatry, University of Maryland School of Medicine, Baltimore, MD, USA.
Shekhar SaxenaGlobal Health and Population, Harvard T H Chan School of Public Health, Boston, MA, USA.
Rajesh TampiDepartment of Psychiatry, Creighton University School of Medicine, Omaha, NE, USA.
Heather LeutwylerDepartment of Physiological Nursing, University of California, San Francisco, CA, USA.
Michael T ComptonDepartment of Psychiatry, Columbia University College of Physicians and Surgeons, New York, NY, USA.
Barton W PalmerDepartment of Psychiatry, University of California, San Diego, CA, USA.
Dilip V JesteDepartment of Psychiatry, University of California, San Diego, CA, USA.
University of California, San Diego · USColorado State University · USColumbia University · USCreighton University · USHarvard Global Health Institute · USHarvard University · USUniversity of California, San Francisco · USUniversity of Maryland, Baltimore · USUniversity of Miami · US

Funding

FELLOWSHIP IN GERIATRIC MENTAL HEALTHT32MH019934 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Elizabeth W Twamley · 1994 to 2026
$9.5M
Loneliness in Aging with SchizophreniaR01MH120201 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI PALMER, BARTON W. · 2020 to 2024
$3.9M
An Adaptive Testing Platform for Optimizing RDoC Experimental Cognitive MeasuresR01MH121546 · NIMH · COLORADO STATE UNIVERSITY · PI THOMAS, MICHAEL L · 2020 to 2024
$2.6M
NIMH NIH HHS R01 MH120201NIMH NIH HHS R01MH120201NIMH NIH HHS R01 MH121546NIMH NIH HHS T32 MH019934
6 · The paper itself

Abstract

backgroundSocial determinants of health (SDoHs) are receiving growing attention and are particularly relevant to persons with schizophrenia-spectrum psychotic disorders (SSPDs), considering their heightened risk of comorbidities, cognitive and functional decline, and early mortality. Yet, we did not find any comprehensive review of multiple SDoHs in SSPD. STUDY

designWe conducted a scoping review of meta-analyses and systematic reviews of nine major SDoHs in SSPD. STUDY

resultsChildhood abuse, parental psychopathology, parental communication problems, bullying, and urban settings with lower socioeconomic status were major risk factors for the greater incidence of SSPD and/or worse health. Social network size was inversely associated with overall psychopathology and negative symptoms. Experiences of racial/ethnic discrimination correlated with the prevalence of psychotic symptoms and experiences. Compared to native populations, the risk of psychosis was higher in immigrants, refugees, and asylees. Social fragmentation was associated with an increased prevalence of schizophrenia. Homeless populations had a 30-fold higher prevalence of schizophrenia than the general population. Seriously mentally ill people were 2.7 times more likely to report food insecurity than controls. The prevalence of non-affective psychosis in prisoners was 2.0%-6.5%, compared to 0.3% in the general population. Certain potentially positive factors like family and community resilience remain poorly studied.

conclusionsSDoHs are associated with higher rates of and worse outcomes in SSPD. Well-designed longitudinal studies are needed to understand SDoHs' contribution to health in persons with SSPD, to develop interventions, and to implement changes in clinical care and public health policies that would reduce adverse health impacts of SDoHs. Positive SDoHs deserve greater attention.

Indexed as

Psychotic DisordersSchizophreniaChildHumansPsychopathologyRisk FactorsSocial Determinants of Healthchildhood traumahomelessnessimmigrationpovertyracismsocial connections

Identifiers

PMID37022779
PMCPMC10318890
OpenAlexW4362658175

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.