Evidence map›Paper›PMID 37022574›Full record

ReviewInflammopharmacology2023

Crosstalk between phytochemicals and inflammatory signaling pathways.

Sonima Prasad, Vishal Kumar, Charan Singh, Arti Singh

Abstract readReview
PubMed Publisher
In one paragraph

Review in Inflammopharmacology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Djulis (Molecules (Basel, Switzerland) · 2025
    Review
  5. Article
  6. Drug design, development and therapy · 2025
    Review
  7. Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Sonima PrasadDepartment of Pharmacology, ISF College of Pharmacy, Moga, 142001, Punjab, India.
Vishal KumarDepartment of Pharmacology, ISF College of Pharmacy, Moga, 142001, Punjab, India.
Charan SinghDepartment of Pharmaceutical Sciences, School of Pharmacy, H.N.B. Garhwal University, Srinagar, Garhwal, 246174, Uttarakhand, India.
Arti SinghDepartment of Pharmacology, ISF College of Pharmacy, Moga, 142001, Punjab, India. artiniper@gmail.com.ORCID http://orcid.org/0000-0001-5168-4930
Indo Soviet Friendship College of Pharmacy · INHemwati Nandan Bahuguna Garhwal University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Novel bioactive constituents from natural sources are actively being investigated. The phytochemicals in these phenolic compounds are believed to have a variety of beneficial effects on human health. Several phenolic compounds have been found in plants. The antioxidant potential of phenols has been discussed in numerous studies along with their anti-inflammatory effects on pro-inflammatory cytokine, inducible cyclooxygenase-2, and nitric oxide synthase. Through current study, an attempt is made to outline and highlight a wide variety of inflammation-associated signaling pathways that have been modified by several natural compounds. These signaling pathways include nuclear factor-kappa B (NF-кB), activator protein (AP)-1, protein tyrosine kinases (PTKs), mitogen-activated protein kinases (MAPKs), nuclear factor erythroid 2-related factor 2 (Nrf2) transcription factors, tyrosine phosphatidylinositol 3-kinase (PI3K)/AKT, and the ubiquitin-proteasome system. In light of the influence of natural substances on signaling pathways, their impact on the production of inflammatory mediator is highlighted in this review.

Indexed as

Phosphatidylinositol 3-KinasesSignal TransductionCyclooxygenase 2HumansLipopolysaccharidesMitogen-Activated Protein KinasesNF-kappa BNitric Oxide Synthase Type IIPhytochemicalsCyclooxygenase 2LipopolysaccharidesMitogen-Activated Protein KinasesNF-kappa BNitric Oxide Synthase Type IIPhosphatidylinositol 3-KinasesPhytochemicalsInflammationInflammatory mediatorsInflammatory signaling pathwayNatural compoundsPhenolic compounds

Identifiers

PMID37022574
OpenAlexW4362657288

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.