Evidence map›Paper›PMID 37022157›Full record

ArticleJournal of clinical microbiology2023

Prospective Genomic Surveillance Reveals Cryptic MRSA Outbreaks with Local to International Origins among NICU Patients.

Jay N Worley, Jessica W Crothers, William J Wolfgang, Sai Laxmi Gubbala Venkata, Maria Hoffmann, Victor Jayeola, Michael Klompas, Marc Allard, Lynn Bry

Open access · greenAbstract read
In one paragraph

Article in Journal of clinical microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 14 citations in OpenAlex.

  1. Optimized Surveillance Testing for ToxigenicmedRxiv : the preprint server for health sciences · 2026
    Article
  2. Article
  3. Article
  4. Gut microbes · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Approaching pathogenicbioRxiv : the preprint server for biology · 2024
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Jay N WorleyMassachusetts Host-Microbiome Center, Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.ORCID 0000-0002-5923-1159
Jessica W CrothersDepartment of Pathology and Laboratory Medicine, University of Vermont Medical Center, Burlington, Vermont, USA.
William J WolfgangWadsworth Center, Division of Infectious Diseases, New York State Department of Health, Albany, New York, USA.ORCID 0000-0003-1769-0215
Sai Laxmi Gubbala VenkataWadsworth Center, Division of Infectious Diseases, New York State Department of Health, Albany, New York, USA.
Maria HoffmannCenter for Food Safety and Nutrition, U.S. Food and Drug Administration, College Park, Maryland, USA.
Victor JayeolaCenter for Food Safety and Nutrition, U.S. Food and Drug Administration, College Park, Maryland, USA.ORCID 0000-0002-1638-4171
Michael KlompasDepartment of Population Medicine, Harvard Medical School, Boston, Massachusetts, USA.
Marc AllardCenter for Food Safety and Nutrition, U.S. Food and Drug Administration, College Park, Maryland, USA.
Lynn BryMassachusetts Host-Microbiome Center, Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.ORCID 0000-0002-8792-8527
Brigham and Women's Hospital · USCenter for Food Safety and Applied Nutrition · USNew York State Department of Health · USUniversity of Vermont · US

Funding

STRUCTURE-FUNCTION RELATIONSHIPS IN THE ALIMENTARY TRACTP30DK034854 · NIDDK · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI JONATHAN C KAGAN · 1986 to 2026
$32.4M
NIDDK NIH HHS P30 DK034854
6 · The paper itself

Abstract

Methicillin-resistant Staphylococcus aureus (MRSA) infections cause substantive morbidity and mortality in neonates. Using publicly available resources from the National Center of Biotechnology Information (NCBI) and Food and Drug Administration's (FDA) GalaxyTrakr pipeline, we illustrate the dynamics of MRSA colonization and infection in neonates. Over 217 days of prospective surveillance, analyses revealed concurrent MRSA transmission chains affecting 11 of 17 MRSA-colonized patients (65%), with two clusters that demonstrated intervals of more than a month among the appearance of isolates. All MRSA infected neonates (

Indexed as

Cross InfectionMethicillin-Resistant Staphylococcus aureusStaphylococcal InfectionsDisease OutbreaksGenomicsHumansInfant, NewbornInfection ControlIntensive Care Units, NeonatalProspective Studiesantibiotic resistancegenomic epidemiologyMRSANICUnosocomial diseasepathogen detectionStaphylococcus aureus

Identifiers

PMID37022157
PMCPMC10204624
OpenAlexW4362658138

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.