Evidence map›Paper›PMID 37021699›Full record

ArticleGlobal public health2023

Roadblocks and resilience: A qualitative study of the impact of pediatric tuberculosis on Tanzanian households and solutions from caregivers.

Kristen Petros de Guex, Domitila Augustino, Paulo Mejan, Rehema Gadiye, Cornel Massong, Saning'o Lukumay, Perry Msoka, Margaretha Sariko, Dafroza Kimathi, Christopher Vinnard and 7 more

Open access · goldAbstract read
In one paragraph

Article in Global public health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Cash transfers to enhance completion of TB screening among household contacts in rural Tanzania.The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease · 2024
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 5 institutions in 2 countries.

Kristen Petros de GuexUniversity of Virginia, Division of Infectious Diseases and International Health, Charlottesville, USA.
Domitila AugustinoHaydom Global Health Research Center, Haydom, Tanzania.
Paulo MejanHaydom Global Health Research Center, Haydom, Tanzania.
Rehema GadiyeHaydom Global Health Research Center, Haydom, Tanzania.
Cornel MassongHaydom Global Health Research Center, Haydom, Tanzania.
Saning'o LukumayHaydom Global Health Research Center, Haydom, Tanzania.
Perry MsokaKilimanjaro Clinical Research Institute, Moshi, Tanzania.
Margaretha SarikoKilimanjaro Clinical Research Institute, Moshi, Tanzania.
Dafroza KimathiKilimanjaro Clinical Research Institute, Moshi, Tanzania.
Christopher VinnardGlaxoSmithKline, Warren, USA.
Yingda XieRutgers New Jersey Medical School, Division of Infectious Diseases, Newark, USA.
Blandina MmbagaKilimanjaro Clinical Research Institute, Moshi, Tanzania.
Herman PfaeffleNavy Medicine & Readiness Training Command, Portsmouth, USA.
Maria GebaUniversity of Virginia, Division of Infectious Diseases and International Health, Charlottesville, USA.
Scott K HeysellUniversity of Virginia, Division of Infectious Diseases and International Health, Charlottesville, USA.
Estomih MdumaHaydom Global Health Research Center, Haydom, Tanzania.
Tania A ThomasUniversity of Virginia, Division of Infectious Diseases and International Health, Charlottesville, USA.
Haydom Lutheran Hospital · TZKilimanjaro Christian Medical Centre · TZUniversity of Virginia · USGlaxoSmithKline (United States) · USRutgers, The State University of New Jersey · US

Funding

INFECTIOUS DISEASES TRAINING PROGRAMT32AI007046 · NIAID · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI Alison K Criss, William A Petri · 1985 to 2026
$15.3M
Urine Colorimetry for Tuberculosis Pharmacokinetics Evaluation in Children and AdultsR01AI137080 · NIAID · UNIVERSITY OF VIRGINIA · PI Scott K Heysell, Leonid Kagan · 2018 to 2026
$6.3M
Biodefense Short-Term Training for Minority StudentT35AI060528 · NIAID · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI HALME, ADRIAN J, PETRI, WILLIAM A · 2004 to 2024
$1.3M
NIAID NIH HHS R01 AI137080NIAID NIH HHS T32 AI007046NIAID NIH HHS T35 AI060528
6 · The paper itself

Abstract

Distinct from quantifying the economic sequelae of tuberculosis (TB) in adults, data are scarce regarding lived experiences of youth and their caregivers seeking and sustaining TB treatment in low income communities. Children ages 4-17 diagnosed with TB and their caregivers were recruited from rural and semi-urban northern Tanzania. Using a grounded theory approach, a qualitative interview guide was developed, informed by exploratory research. Twenty-four interviews were conducted in Kiswahili, audio-recorded and analyzed for emerging and consistent themes. Dominant themes found were socioemotional impacts of TB on households, including adverse effects on work productivity, and facilitators and obstacles to TB care, including general financial hardship and transportation challenges. The median percentage of household monthly income spent to attend a TB clinic visit was 34% (minimum: 1%, maximum: 220%). The most common solutions identified by caregivers to mitigate adverse impacts were transportation assistance and nutrition supplementation. To end TB, healthcare systems must acknowledge the total financial burden shouldered by low wealth families seeking pediatric TB care, provide consultations and medications locally, and increase access to TB-specific communal funds to mitigate burdens such as inadequate nutrition.

Indexed as

CaregiversTuberculosisAdolescentAdultChildChild, PreschoolHumansIncomeProspective StudiesTanzaniaCatastrophic costscoping behaviorsfamilygrounded theory

Identifiers

PMID37021699
PMCPMC10228591
OpenAlexW4362657575

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.