Evidence map›Paper›PMID 37021351›Full record

ArticleEuropace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology2023

Clinical controversy: methodology and indications of cardioneuroablation for reflex syncope.

Michele Brignole, Tolga Aksu, Leonardo Calò, Philippe Debruyne, Jean Claude Deharo, Alessandra Fanciulli, Artur Fedorowski, Piotr Kulakowski, Carlos Morillo, Angel Moya and 4 more

Abstract read
In one paragraph

Article in Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Peri-procedure and Mid-Long Term Effects of Pulsed Field Ablation vs. Thermal Ablation (Cryo- or Radiofrequency) on Autonomic Nervous System Function in Atrial Fibrillation: A Systematic and Quantitative Pooled-Analysis with Potential Implications for Patient Selection (The PULSE-COLD-HEAT-ANS Collaboration).Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2025
    Pooled it
  2. Cardioneuroablation for the treatment of reflex syncope and functional bradyarrhythmias: A Scientific Statement of the European Heart Rhythm Association (EHRA) of the ESC, the Heart Rhythm Society (HRS), the Asia Pacific Heart Rhythm Society (APHRS) and the Latin American Heart Rhythm Society (LAHRS).Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2024
    Guideline
  3. Review
  4. Article
  5. Differential effects of right atrial ablation sites on vagal modulation of the sinus node during cardioneuroablation.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2026
    Article
  6. A tailored approach to cardioneuroablation for reflex syncope and functional bradycardia: results from the ELEGANCE multicentre study.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2026
    Article
  7. Older age is not an independent predictor of syncope recurrence following cardioneuroablation for reflex syncope.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2026
    Observational
  8. Intracardiac echocardiography guided anatomical approach to cardioneuroablation: feasibility and outcomes.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2025
    Article
  9. Article
  10. Article
  11. Article
  12. Translational approach to ventricular innervation: the posterior descending ganglionated plexus.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2025
    Article
  13. Article
  14. Article
  15. Review
  16. Review
  17. Article
  18. Observational
  19. Cardioneuroablation for treatment of atrioventricular block: to cure the patient or the electrocardiogram?Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2024
    Article
  20. Procedural and Intermediate-term Results of the Electroanatomical-guided Cardioneuroablation for the Treatment of Supra-Hisian Second- or Advanced-degree Atrioventricular Block: the PIRECNA multicentre registry.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2024
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors.

Michele BrignoleIRCCS Istituto Auxologico Italiano, Faint & Fall Programme, Ospedale San Luca, Piazzale Brescia 2, 20149 Milano, Italy.ORCID 0000-0002-1845-5607
Tolga AksuDepartment of Cardiology, Yeditepe University Hospital, 34755 Ataşehir/İstanbul, Turkey.ORCID 0000-0001-8061-9660
Leonardo CalòDepartment of Cardiology, Policlinico Casilino, 00169 Roma, Italy.ORCID 0000-0002-6062-5286
Philippe DebruyneDepartment of Cardiology, Imeldaziekenhuis, 2820 Bonheiden, Belgium.ORCID 0000-0002-2854-4179
Jean Claude DeharoAssistance Publique - Hôpitaux de Marseille, Centre Hospitalier Universitaire La Timone, Service de Cardiologie, France and Aix Marseille Université, C2VN, 13005 Marseille, France.ORCID 0000-0002-1534-3845
Alessandra FanciulliDepartment of Neurology, Medical University of Innsbruck, 6020 Innsbruck, Austria.
Artur FedorowskiDepartment of Cardiology, Karolinska University Hospital, 17177 Stockholm, Sweden.ORCID 0000-0002-5352-6327
Piotr KulakowskiCentre of Postgraduate Medical Education, Department of Cardiology, Grochowski Hospital, 04-073 Warsaw, Poland.
Carlos MorilloDepartment of Cardiac Sciences, Libin Cardiovascular Institute, Cumming School of Medicine, University of Calgary, T2N 1N4 Calgary, AB, Canada.ORCID 0000-0002-8739-2099
Angel MoyaDepartment of Cardiology, Hospital Universitari Dexeus, 08028 Barcelona, Spain.
Brian OlshanskyDivision of Cardiology, University of Iowa Hospitals, 52242 Iowa City, IA, USA.ORCID 0000-0002-6044-045X
Roman PiotrowskiCentre of Postgraduate Medical Education, Department of Cardiology, Grochowski Hospital, 04-073 Warsaw, Poland.ORCID 0000-0001-8034-4898
Sebastian StecDivision of Electrophysiology, Cardioneuroablation, Cardioneuroablation, Catheter Ablation and Cardiac Stimulation, Subcarpathian Center for Cardiovascular Intervention, 38-500 Sanok, Poland.ORCID 0000-0002-9862-318X
Dan WichterleDepartment of Cardiology, Institute for Clinical and Experimental Medicine (IKEM), 11336 Prague, Czechia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Syncope, VasovagalBradycardiaHumansReflexCatheter ablationMethodsNeurally mediated syncopeReflex syncopeSyncopeVasovagal syncope

Identifiers

PMID37021351
PMCPMC10227654

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.