ArticleJournal of dental sciences2023
Higher frequencies of anemia, vitamin B12 deficiency, and gastric parietal cell antibody positivity in folic acid-deficient Taiwanese male oral submucous fibrosis patients.
Article in Journal of dental sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 12 citations in OpenAlex.
- Anemia, hematinic deficiencies, and hyperhomocysteinemia in younger and older oral lichen planus patients.Journal of dental sciences · 2026Article
- Higher serum gastric parietal cell antibody titers are associated with increased frequencies of macrocytosis, vitamin B12 deficiency, and hyperhomocysteinemia in patients with oral lichen planus.Journal of dental sciences · 2026Article
- Gastric parietal cell and thyroid autoantibodies in patients with oral lichen planus.Journal of dental sciences · 2026Article
- The presence of thyroid autoantibodies is not associated with anemia, hematinic deficiencies, and hyperhomocysteinemia in oral lichen planus patients.Journal of dental sciences · 2026Article
- Prevalences of vitamin B12 deficiency, pernicious anemia, macrocytosis, and hyperhomocysteinemia in 532 serum gastric parietal cell antibody-positive oral mucosal disease patients.Journal of dental sciences · 2026Article
- Anemia, hematinic deficiencies, hyperhomocysteinemia, and serum gastric parietal cell antibody positivity in oral lichen planus patients with macrocytosis.Journal of dental sciences · 2025Article
- Anemia, hematinic deficiencies, hyperhomocysteinemia, and gastric parietal cell antibody positivity in oral lichen planus patients with normocytosis.Journal of dental sciences · 2025Article
- Anemia, hematinic deficiencies, and hyperhomocysteinemia in gastric parietal cell antibody-positive and -negative oral lichen planus patients.Journal of dental sciences · 2025Article
- Anemia, hematinic deficiencies, and gastric parietal cell antibody positivity in oral lichen planus patients with or without hyperhomocysteinemia.Journal of dental sciences · 2025Article
- Anemia, hematinic deficiencies, hyperhomocysteinemia, and gastric parietal cell antibody positivity in oral lichen planus patients with or without microcytosis.Journal of dental sciences · 2025Article
- Anemia, hematinic deficiencies, hyperhomocysteinemia, and gastric parietal cell antibody positivity in oral lichen planus patients with iron deficiency.Journal of dental sciences · 2025Article
- Anemia, hematinic deficiencies, hyperhomocysteinemia, and serum gastric parietal cell antibody positivity in oral lichen planus patients with vitamin B12 deficiency.Journal of dental sciences · 2025Article
- Anemia, hematinic deficiencies, and hyperhomocysteinemia in male and female oral lichen planus patients.Journal of dental sciences · 2025Article
- Anemia, hematinic deficiencies, hyperhomocysteinemia, and serum gastric parietal cell antibody positivity in 588 patients with oral lichen planus.Journal of dental sciences · 2025Article
- Iron-related Biomarkers in the Diagnosis and Management of Iron Disorders.Current medicinal chemistry · 2024Review
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background/purpose: Oral submucous fibrosis (OSF) is a progressive fibrotic oral mucosal disease associated with betel quid chewing. This study evaluated whether Taiwanese male OSF patients with folic acid (FA) deficiency (the serum FA level ≤6 ng/mL, so-called FA-deficient OSF patients) had high frequencies of blood hemoglobin (Hb) and serum iron and vitamin B12 deficiencies, and serum gastric parietal cell antibody (GPCA) positivity. Materials and methods: The blood Hb and serum iron, vitamin B12, FA, and GPCA concentrations in 59 Taiwanese male FA-deficient OSF patients were measured and compared with the corresponding data in 118 age-matched healthy male control subjects. Results: We found that 3 (5.1%), 35 (59.3%), and 7 (11.9%) of the 59 FA-deficient OSF patients had blood Hb (<13 g/dL) and serum vitamin B12 (≤450 pg/mL) deficiencies, and serum GPCA positivity, respectively. Furthermore, 59 FA-deficient OSF patients had significantly higher frequencies of serum vitamin B12 deficiency and serum GPCA positivity than 118 healthy control subjects (all Conclusion: We conclude that Taiwanese male FA-deficient OSF patients have high frequencies of serum vitamin B12 deficiency and GPCA positivity than healthy control subjects. The vitamin B12 and FA deficiencies in FA-deficient OSF patients are more likely due to OSF symptoms and signs-caused insufficient intake, difficulty in chewing and swallowing, and malabsorption of food fragment-bound vitamin B12 and FA rather than the GPCA positivity in these OSF patients.
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