Evidence map›Paper›PMID 37021198›Full record

SynthesisEuropean stroke journal2023

Prolonged cardiac monitoring for stroke prevention: A systematic review and meta-analysis of randomized-controlled clinical trials.

Georgios Tsivgoulis, Lina Palaiodimou, Sokratis Triantafyllou, Martin Köhrmann, Polychronis Dilaveris, Konstantinos Tsioufis, Gkikas Magiorkinis, Christos Krogias, Peter D Schellinger, Valeria Caso and 8 more

Open access · bronzeAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in European stroke journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.

  1. Guideline
  2. Review
  3. Cryptogenic stroke in women: impact of insertable cardiac monitoring in the STROKEWISE cohort study.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2026
    Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Observational
  13. Review
  14. Article
  15. Review
  16. [Secondary prophylaxis of ischemic stroke].Innere Medizin (Heidelberg, Germany) · 2023
    Article
  17. Neurological update: neuro-otology 2023.Journal of neurology · 2023
    Article
  18. Article
  19. Review
  20. Discrepant Outcomes of Direct Oral Anticoagulant Trials in Device-Detected Atrial Fibrillation after Stroke: Insights from NOAH-AFNET 6 and ARTESIA.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 11 institutions in 7 countries.

Georgios TsivgoulisSecond Department of Neurology, "Attikon" University Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.ORCID 0000-0002-0640-3797
Lina PalaiodimouSecond Department of Neurology, "Attikon" University Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.ORCID 0000-0001-7757-609X
Sokratis TriantafyllouSecond Department of Neurology, "Attikon" University Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.
Martin KöhrmannDepartment of Neurology, Universitätsklinikum Essen, Essen, Germany.
Polychronis DilaverisFirst Department of Cardiology, National and Kapodistrian University of Athens, School of Medicine, Hippokration Hospital, Athens, Greece.
Konstantinos TsioufisFirst Department of Cardiology, National and Kapodistrian University of Athens, School of Medicine, Hippokration Hospital, Athens, Greece.
Gkikas MagiorkinisDepartment of Hygiene, Epidemiology and Medical Statistics, Medical School, National and Kapodistrian University of Athens, Athens, Greece.
Christos KrogiasDepartment of Neurology, St. Josef-Hospital, Ruhr University, Bochum, Germany.
Peter D SchellingerDepartment of Neurology and Neurogeriatry, Johannes Wesling Medical Center, Ruhr University Bochum, Minden, Germany.
Valeria CasoStroke Unit, Santa Maria Della Misericordia Hospital, University of Perugia, Perugia, Italy.
Maurizio PaciaroniStroke Unit, Santa Maria Della Misericordia Hospital, University of Perugia, Perugia, Italy.
Mukul SharmaDivision of Neurology, McMaster University and Population Health Research Institute, Hamilton, ON, Canada.
Robin LemmensDepartment of Neurosciences, Experimental Neurology and Leuven Research Institute for Neuroscience and Disease (LIND), KU Leuven - University of Leuven, Leuven, Belgium.
David J GladstoneSunnybrook Research Institute and Hurvitz Brain Sciences Program, Sunnybrook Health Sciences Centre, Toronto, ON, Canada.
Tommaso SannaFondazione Policlinico Gemelli IRCCS, Rome, Italy.
Rolf WachterDepartment of Cardiology, University Hospital Leipzig, Leipzig, Germany.
Gerasimos FilippatosSecond Department of Cardiology, National and Kapodistrian University of Athens, School of Medicine, Athens, Greece.
Aristeidis H KatsanosDivision of Neurology, McMaster University and Population Health Research Institute, Hamilton, ON, Canada.
National and Kapodistrian University of Athens · GRPopulation Health Research Institute · CAUniversity of Perugia · ITEssen University Hospital · DEJohannes Wesling Klinikum Minden · DESt. Josef-Hospital · DESunnybrook Health Science Centre · CAUniversità Cattolica del Sacro Cuore · ITUniversitätsmedizin Göttingen · DEUniversity of Tennessee Health Science Center · USVIB-KU Leuven Center for Brain & Disease Research · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Prolonged cardiac monitoring (PCM) substantially improves the detection of subclinical atrial fibrillation (AF) among patients with history of ischemic stroke (IS), leading to prompt initiation of anticoagulants. However, whether PCM may lead to IS prevention remains equivocal. Patients and methods: In this systematic review and meta-analysis, randomized-controlled clinical trials (RCTs) reporting IS rates among patients with known cardiovascular risk factors, including but not limited to history of IS, who received PCM for more than 7 days versus more conservative cardiac rhythm monitoring methods were pooled. Results: Seven RCTs were included comprising a total of 9048 patients with at least one known cardiovascular risk factor that underwent cardiac rhythm monitoring. PCM was associated with reduction of IS occurrence compared to conventional monitoring (Risk Ratio: 0.76; 95% CI: 0.59-0.96; Conclusion: PCM may represent an effective stroke prevention strategy in selected patients. Additional RCTs are warranted to validate the robustness of the reported associations.

Indexed as

Atrial FibrillationIschemic Attack, TransientIschemic StrokeStrokeAnticoagulantsHemorrhageHumansAnticoagulantsanticoagulationatrial fibrillationimplantable cardiac monitorpreventionprolonged cardiac monitoringStroke

Identifiers

PMID37021198
PMCPMC10069201
OpenAlexW4309756545

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.