Evidence map›Paper›PMID 37021170›Full record

Observational studyEuropean stroke journal2023

Ability of patients with acute ischemic stroke to recall given information on intravenous thrombolysis: Results of a prospective multicenter study.

Luzie Schuster, Fabian Essig, Naeimeh Daneshkhah, Juliane Herm, Simon Hellwig, Matthias Endres, Ulrich Dirnagl, Frank Hoffmann, Dominik Michalski, Waltraud Pfeilschifter and 5 more

Abstract readObservational StudyMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in European stroke journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Luzie SchusterDepartment of Neurology, University of Leipzig, Leipzig, Germany.ORCID 0000-0002-6342-1641
Fabian EssigDepartment of Neurology, Universitätsklinikum Würzburg, Würzburg, Germany.
Naeimeh DaneshkhahDepartment of Neurology, Universitätsklinikum Würzburg, Würzburg, Germany.
Juliane HermKlinik und Hochschulambulanz für Neurologie, Charité - Universitätsmedizin Berlin, Berlin, Germany.
Simon HellwigKlinik und Hochschulambulanz für Neurologie, Charité - Universitätsmedizin Berlin, Berlin, Germany.
Matthias EndresKlinik und Hochschulambulanz für Neurologie, Charité - Universitätsmedizin Berlin, Berlin, Germany.
Ulrich DirnaglKlinik und Hochschulambulanz für Neurologie, Charité - Universitätsmedizin Berlin, Berlin, Germany.
Frank HoffmannDepartment of Neurology, Martha-Maria Hospital, Halle/Saale, Germany.
Dominik MichalskiDepartment of Neurology, University of Leipzig, Leipzig, Germany.
Waltraud PfeilschifterDepartment of Neurology, University of Frankfurt, Frankfurt/Main, Germany.
Christian UrbanekDepartment of Neurology, Hospital Ludwigshafen, Ludwigshafen am Rhein, Germany.
Gabor C PetzoldDivision of Vascular Neurology, Department of Neurology, University of Bonn, Bonn, Germany.
Timolaos RizosDepartment of Neurology, University of Heidelberg, Heidelberg, Germany.ORCID 0000-0002-7250-4668
Andrea KraftDepartment of Neurology, Martha-Maria Hospital, Halle/Saale, Germany.
Karl Georg HaeuslerDepartment of Neurology, Universitätsklinikum Würzburg, Würzburg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Intravenous thrombolysis (IVT) is an on label treatment for selected patients with acute ischemic stroke (AIS). As major bleeding or allergic shock may occur, the need to ensure patients' informed consent for IVT is a matter of debate. Patients and methods: Prospective investigator-initiated multi-center observational study to assess the ability of AIS patients to recall information, provided by a physician during a standardized educational talk (SET) on IVT use. The recall of 20 pre-defined items was assessed in AIS after 60-90 min ( Results: Within 60-90 min after SET, AIS patients (median age 70 years, 31% female, median NIHSS score on admission 3 points) who were considered capable to provide informed consent recalled 55% (IQR 40%-66.7%) of the provided SET items. In multivariable linear regression analysis recapitulation by AIS patients was associated with their educational level (β = 6.497, Conclusion: AIS patients eligible for IVT remember about half of all SET-items after 60-90 min or 23-25 h, respectively. The fact that the recapitulation of IVT-associated risks is particularly poor should be given special consideration.

Indexed as

Brain IschemiaIschemic StrokeStrokeAgedFemaleFibrinolytic AgentsHumansMaleProspective StudiesThrombolytic TherapyTreatment OutcomeFibrinolytic Agentsalteplaseinformed consentintracranial bleedingIschemic strokert-PA

Identifiers

PMID37021170
PMCPMC10069168

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.