Evidence map›Paper›PMID 37021154›Full record

ArticleEuropean stroke journal2023

VPS dependency after aneurysmal subarachnoid haemorrhage and influence of admission hyperglycaemia.

Isabel Charlotte Hostettler, Nicole Lange, Nina Schwendinger, Gareth Ambler, Theresa Hirle, Samira Frangoulis, Dominik Trost, Jens Gempt, Kornelia Kreiser, Bernhard Meyer and 2 more

Open access · bronzeAbstract read
In one paragraph

Article in European stroke journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Observational
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 5 countries.

Isabel Charlotte HostettlerDepartment of Neurosurgery, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.ORCID 0000-0002-9004-2540
Nicole LangeDepartment of Neurosurgery, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.
Nina SchwendingerDepartment of Neurosurgery, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.
Gareth AmblerDepartment of Statistical Science, University College London, London, UK.
Theresa HirleDepartment of Neurosurgery, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.ORCID 0000-0001-8662-8891
Samira FrangoulisDepartment of Neurosurgery, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.
Dominik TrostDepartment of Neuroradiology, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.ORCID 0000-0003-4042-2999
Jens GemptDepartment of Neurosurgery, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.
Kornelia KreiserDepartment of Neuroradiology, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.
Bernhard MeyerDepartment of Neurosurgery, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.
Christof WinterInstitute of Clinical Chemistry and Pathobiochemistry, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.
Maria WostrackDepartment of Neurosurgery, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.
TUM Klinikum · DERoyal Statistical Society · GBUniversity of St.Gallen · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Hydrocephalus after aneurysmal subarachnoid haemorrhage (aSAH) is a common complication which may lead to insertion of a ventriculoperitoneal shunt (VPS). Our aim is to evaluate a possible influence of specific clinical and biochemical factors on VPS dependency with special emphasis on hyperglycaemia on admission. Patients and methods: Retrospective analysis of a monocentric database of aSAH patients. Using univariable and multivariable logistic regression analysis we evaluated factors influencing VPS dependency, with a special focus on hyperglycaemia on blood sample within 24 h of admission, dichotomised at 126 mg/dl. Factors evaluated in the univariable analysis were age, sex, known diabetes, Hunt and Hess grade, Barrow Neurological Institute scale, treatment modality, extra-ventricular drain (EVD) insertion, complications (rebleeding, vasospasm, infarction, decompressive craniectomy, ventriculitis), outcome variables and laboratory parameters (glucose, C-reactive protein, procalcitonin). Results: We included 510 consecutive patients treated with acute aSAH requiring a VPS (mean age 58.2 years, 66% were female). An EVD was inserted in 387 (75.9%) patients. In the univariable analysis, VPS dependency was associated with hyperglycaemia on admission (OR 2.56, 95%CI 1.58-4.14, Conclusion: Hyperglycaemia on admission was associated with an increased probability of VPS placement. If confirmed, this finding might facilitate treatment of these patients by accelerating insertion of a permanent draining system.

Indexed as

Cerebral VentriculitisGastritisHyperglycemiaSubarachnoid HemorrhageFemaleHumansMaleMiddle AgedRetrospective StudiesVentriculoperitoneal ShuntAneurysmal subarachnoid haemorrhagehydrocephalushyperglycaemiarisk factorsVPS dependency

Identifiers

PMID37021154
PMCPMC10069185
OpenAlexW4313290117

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.