Evidence map›Paper›PMID 37021108›Full record

ArticleIEEE transactions on radiation and plasma medical sciences2023

Training End-to-End Unrolled Iterative Neural Networks for SPECT Image Reconstruction.

Zongyu Li, Yuni K Dewaraja, Jeffrey A Fessler

Abstract read
In one paragraph

Article in IEEE transactions on radiation and plasma medical sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Review
  2. Article
  3. AI in SPECT Imaging: Opportunities and Challenges.Seminars in nuclear medicine · 2025
    Review
  4. Review
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. AI for PET image reconstruction.The British journal of radiology · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Zongyu LiDepartment of Electrical Engineering and Computer Science, University of Michigan.
Yuni K DewarajaDepartment of Radiology, University of Michigan.
Jeffrey A FesslerDepartment of Electrical Engineering and Computer Science, University of Michigan.

Funding

Imaging and Dosimetry of Yttrium-90 for Personalized Cancer TreatmentR01EB022075 · NIBIB · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI DEWARAJA, YUNI K · 2016 to 2023
$4.7M
Bringing Capacity for Theranostic Dosimetry Planning to the Nuclear Medicine ClinicR01CA240706 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI DEWARAJA, YUNI K · 2020 to 2024
$3.0M
NCI NIH HHS R01 CA240706NIBIB NIH HHS R01 EB022075
6 · The paper itself

Abstract

Training end-to-end unrolled iterative neural networks for SPECT image reconstruction requires a memory-efficient forward-backward projector for efficient backpropagation. This paper describes an open-source, high performance Julia implementation of a SPECT forward-backward projector that supports memory-efficient backpropagation with an exact adjoint. Our Julia projector uses only ~5% of the memory of an existing Matlab-based projector. We compare unrolling a CNN-regularized expectation-maximization (EM) algorithm with end-to-end training using our Julia projector with other training methods such as gradient truncation (ignoring gradients involving the projector) and sequential training, using XCAT phantoms and virtual patient (VP) phantoms generated from SIMIND Monte Carlo (MC) simulations. Simulation results with two different radionuclides (

Indexed as

backpropagatable forward-backward projectorEnd-to-end learningquantitative SPECTregularized model-based image reconstruction

Identifiers

PMID37021108
PMCPMC10072846

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.