Evidence map›Paper›PMID 37021063›Full record

ReviewCureus2023

An Analysis of Lidocaine Usage in the Treatment of Squamous Cell Carcinoma.

Maya Maalouf, Akshay J Reddy, Pasha Mazboudi, Mildred Min, Rushil Rawal, Casey A Curow, Monica E Guirgus, Danny S Abdalnour, Telak Brahmbhatt, Rakesh Patel

Open access · diamondAbstract readReview
In one paragraph

Review in Cureus, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Maya MaaloufMedicine, California University of Science and Medicine, Colton, USA.
Akshay J ReddyMedicine, California University of Science and Medicine, Colton, USA.
Pasha MazboudiMedicine, California University of Science and Medicine, Colton, USA.
Mildred MinDermatology, California Northstate University College of Medicine, Elk Grove, USA.
Rushil RawalMedicine, California University of Science and Medicine, Colton, USA.
Casey A CurowMedicine, California University of Science and Medicine, Colton, USA.
Monica E GuirgusMedicine, California University of Science and Medicine, Colton, USA.
Danny S AbdalnourMedicine, California University of Science and Medicine, Colton, USA.
Telak BrahmbhattHealth Sciences, California Northstate University, Rancho Cordova, USA.
Rakesh PatelInternal Medicine, East Tennessee State University, Quillen College of Medicine, Johnson City, USA.
General Tire (United States) · USEast Tennessee State University · USCalifornia Northstate University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Squamous cell carcinoma (SCC) is a form of skin cancer that can be treated using a procedure known as Mohs surgery. Mohs surgery is a safe and effective procedure for eliminating SCC. This surgery requires the usage of an analgesic known as lidocaine. Additional anesthetics were also reported to be necessary for this procedure to be conducted in a manner that significantly minimizes patient harm. According to the review, it was found that SCC was treated with lidocaine as a topical analgesic outside of Mohs surgery. This review analyzes the usage of lidocaine in the treatment of SCC. It was also discovered that lidocaine, as an agent, has the potential to slow the progression of SCC, but more research is needed to see if this is truly the case. On average, it was reported that the concentration of lidocaine used in the in vivo studies was significantly higher than that in the in vitro investigations. Further exploration may be needed to verify the conclusions that were based on the analysis of the papers within the review.

Indexed as

cancer treatmentlidocainemohs surgerysquamous cell carcinomaxylocaine

Identifiers

PMID37021063
PMCPMC10069794
OpenAlexW4322621979

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.