Evidence map›Paper›PMID 37021012›Full record

ArticleHealth science reports2023

Blood pressure-lowering medication prescribing, its adherence to guidelines and relationship with blood pressure control at a family medicine department.

Mark Amankwa Harrison, Afia F A Marfo, Kwame O Buabeng, Augustine Annan, Frempomaa Nelson, Dorcas P Boateng, Florence A Nkansah, Grace Owusu Aboagye, Daniel Ankrah

Abstract read
In one paragraph

Article in Health science reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

9 authors.

Mark Amankwa HarrisonPharmacy Department Korle Bu Teaching Hospital Accra Ghana.ORCID https://orcid.org/0000-0002-8774-1324
Afia F A MarfoDepartment of Pharmacy Practice, College of Health Sciences, Faculty of Pharmacy and Pharmaceutical Sciences Kwame Nkrumah University of Science and Technology Kumasi Ghana.
Kwame O BuabengDepartment of Pharmacy Practice, College of Health Sciences, Faculty of Pharmacy and Pharmaceutical Sciences Kwame Nkrumah University of Science and Technology Kumasi Ghana.
Augustine AnnanPharmacy Department Korle Bu Teaching Hospital Accra Ghana.
Frempomaa NelsonPharmacy Department Korle Bu Teaching Hospital Accra Ghana.
Dorcas P BoatengPharmacy Department Korle Bu Teaching Hospital Accra Ghana.
Florence A NkansahPharmacy Department Korle Bu Teaching Hospital Accra Ghana.
Grace Owusu AboagyePharmacy Department Korle Bu Teaching Hospital Accra Ghana.
Daniel AnkrahPharmacy Department Korle Bu Teaching Hospital Accra Ghana.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: In many resource-constrained countries, control of blood pressure (BP) is low. Antihypertensive drug prescribing practices may influence BP control. However, adherence of prescribing to treatment guidelines may not be optimal in resource-constrained settings. The aim of this study was to evaluate the pattern of blood pressure-lowering medication prescribing, and how it adheres to treatment guidelines, and to identify the relationship between medication prescriptions and BP control. Methods: It was a cross-sectional study of hypertensive outpatients at the Korle Bu Teaching Hospital (KBTH) Family Medicine department (FMD)/Polyclinic. Data was collected with a validated structured form. Adherence of "prescribing" to recommendations of the 2017 Standard Treatment Guidelines of Ghana and 2018 European Society of Cardiology guidelines was assessed using a composite measure. We analyzed data with SPSS. Results: About 81% (247/304) of patients received two or more antihypertensive drugs. Most patients (41%; 267/651) received calcium channel blockers (CCB), and 21.8% (142/651), 15.7% (102/651) and 12.7% (83/651) were on diuretics, angiotensin-receptor blockers (ARBs) and angiotensin converting enzyme (ACE) inhibitors respectively. CCB plus RAS inhibitor (50%) was the most prescribed two-drug combination. Number of BP drugs per patient had a statistically significant inverse relationship with BP control (beta Coefficient = -0.402; 95% Cl: 1.252-2.470; Conclusion: Most patients received multiple-pill combination treatment, and overall adherence to guidelines was suboptimal, largely owing to complex drug therapy. Number of drugs predicted BP control. Our findings suggest a need to prioritize simplified treatment, and implement other strategies to improve hypertension guideline adherence. Further research on the influence of SPC on BP control may inform future hypertension guidelines in Ghana and elsewhere in Africa.

Indexed as

blood pressure controlblood pressure‐lowering medicationfamily medicineGhanaguideline adherencehypertension treatment

Identifiers

PMID37021012
PMCPMC10069237

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.