Evidence map›Paper›PMID 37020954›Full record

ArticleiScience2023

Association of branched-chain amino acids with mortality-the Ludwigshafen Risk and Cardiovascular Health (LURIC) study.

Angela P Moissl, Stefan Lorkowski, Andreas Meinitzer, Stefan Pilz, Hubert Scharnagl, Graciela E Delgado, Marcus E Kleber, Bernhard K Krämer, Burkert Pieske, Martin R Grübler and 6 more

Open access · goldAbstract read
In one paragraph

Article in iScience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 4 institutions in 2 countries.

Angela P MoisslInstitute of Nutritional Sciences Friedrich Schiller University Jena, Jena, Germany.
Stefan LorkowskiInstitute of Nutritional Sciences Friedrich Schiller University Jena, Jena, Germany.
Andreas MeinitzerClinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Graz, Austria.
Stefan PilzMedical University of Graz, Department of Internal Medicine, Division of Endocrinology and Diabetology, Graz, Austria.
Hubert ScharnaglClinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Graz, Austria.
Graciela E DelgadoVth Department of Medicine (Nephrology, Hypertensiology, Endocrinology, Diabetology, Rheumatology, Pneumology), Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
Marcus E KleberCompetence Cluster for Nutrition and Cardiovascular Health (nutriCARD) Halle-Jena-Leipzig, Jena, Germany.
Bernhard K KrämerVth Department of Medicine (Nephrology, Hypertensiology, Endocrinology, Diabetology, Rheumatology, Pneumology), Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
Burkert PieskeDepartment of Internal Medicine and Cardiology, Charitè Campus Virchow Klinikum, Berlin, Germany.
Martin R GrüblerMedical University of Graz, Department of Internal Medicine, Division of Endocrinology and Diabetology, Graz, Austria.
Helmut BrusseeMedical University of Graz, Department of Internal Medicine, Division of Endocrinology and Diabetology, Graz, Austria.
Dirk von LewinskiMedical University of Graz, Department of Internal Medicine, Division of Cardiology, Graz, Austria.
Hermann ToplakMedical University of Graz, Department of Internal Medicine, Division of Endocrinology and Diabetology, Graz, Austria.
Astrid Fahrleitner-PammerMedical University of Graz, Department of Internal Medicine, Division of Endocrinology and Diabetology, Graz, Austria.
Winfried MärzCompetence Cluster for Nutrition and Cardiovascular Health (nutriCARD) Halle-Jena-Leipzig, Jena, Germany.
Andreas TomaschitzHealth Centre Trofaiach, Trofaiach, Austria.
Medical University of Graz · ATHeidelberg University · DEFriedrich Schiller University Jena · DEGerman Centre for Cardiovascular Research · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Branched-chain amino acids (BCAAs) are effectors of metabolic diseases, but their impact on mortality is largely unknown. We investigated the association of BCAA with risk factors and mortality in 2,236 participants of the Ludwigshafen Risk and Cardiovascular Health (LURIC) study using linear and Cox regression. Adiponectin, hemoglobin, C-peptide, hemoglobin A

Indexed as

Association analysisCardiovascular medicineHealth sciences

Identifiers

PMID37020954
PMCPMC10067756
OpenAlexW4328137211

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.