Evidence map›Paper›PMID 37020835›Full record

ArticleERJ open research2023

Prevalence and management of severe asthma in the Nordic countries: findings from the NORDSTAR cohort.

Susanne Hansen, Anna von Bülow, Patrik Sandin, Olivia Ernstsson, Christer Janson, Lauri Lehtimäki, Hannu Kankaanranta, Charlotte Ulrik, Bernt Bøgvald Aarli, Hanna Fues Wahl and 18 more

Open access · goldAbstract read
In one paragraph

Article in ERJ open research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
6.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.

  1. Epidemiology of severe asthma in children: a systematic review and meta-analysis.European respiratory review : an official journal of the European Respiratory Society · 2024
    Pooled it
  2. Trial
  3. Article
  4. Observational
  5. From mild-to-moderate to severe asthma: risk factors and patient profiles from the NORDSTAR cohort.American journal of respiratory and critical care medicine · 2026
    Observational
  6. Cumulative genetic risk for asthma contributes to disease severity in children with asthma.The journal of allergy and clinical immunology. Global · 2026
    Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Association of Obesity and Severe Asthma in Adults.Journal of clinical medicine · 2024
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

28 authors at 17 institutions in 7 countries.

Susanne HansenRespiratory Research Unit, Department of Respiratory Medicine and Infectious Diseases, Bispebjerg Hospital, Copenhagen, Denmark.ORCID https://orcid.org/0000-0002-9550-6703
Anna von BülowRespiratory Research Unit, Department of Respiratory Medicine and Infectious Diseases, Bispebjerg Hospital, Copenhagen, Denmark.
Patrik SandinQuantify Research, Stockholm, Sweden.
Olivia ErnstssonQuantify Research, Stockholm, Sweden.
Christer JansonDepartment of Medical Sciences: Respiratory, Allergy and Sleep Research, Uppsala University, Uppsala, Sweden.ORCID https://orcid.org/0000-0001-5093-6980
Lauri LehtimäkiAllergy Centre, Tampere University Hospital, Tampere, Finland.ORCID https://orcid.org/0000-0003-1586-4998
Hannu KankaanrantaFaculty of Medicine and Health Technology, Tampere University, Tampere, Finland.ORCID https://orcid.org/0000-0001-5258-0906
Charlotte UlrikRespiratory Research Unit, Department of Respiratory Medicine, Copenhagen University Hospital - Hvidovre, Copenhagen, Denmark.ORCID https://orcid.org/0000-0001-8689-3695
Bernt Bøgvald AarliDepartment of Clinical Science, University of Bergen, Bergen, Norway.
Hanna Fues WahlQuantify Research, Stockholm, Sweden.
Kirk GealeQuantify Research, Stockholm, Sweden.ORCID https://orcid.org/0000-0001-7241-8471
Sheila Tuyet TangSanofi, Copenhagen, Denmark.
Maija WolfNovartis Finland, Espoo, Finland.
Tom LarsenNovartis Norway, Oslo, Norway.
Alan AltrajaDepartment of Pulmonology, University of Tartu, Tartu, Estonia.ORCID https://orcid.org/0000-0001-7798-9871
Helena BackmanDepartment of Public Health and Clinical Medicine, Section for Sustainable Health, Umeå University, Umeå, Sweden.ORCID https://orcid.org/0000-0002-0553-8067
Maritta KilpeläinenDivision of Medicine, Department of Pulmonary Diseases, Turku University Hospital, Turku, Finland.
Arja ViinanenDivision of Medicine, Department of Pulmonary Diseases, Turku University Hospital, Turku, Finland.ORCID https://orcid.org/0000-0003-4990-6228
Dora LudviksdottirLandspitali University Hospital and University of Iceland, Reykjavik, Iceland.
Paula KauppiHeart and Lung Center, Department of Pulmonary Diseases, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.
Asger SverrildRespiratory Research Unit, Department of Respiratory Medicine and Infectious Diseases, Bispebjerg Hospital, Copenhagen, Denmark.
Sverre LehmannDepartment of Clinical Science, University of Bergen, Bergen, Norway.
Vibeke BackerDepartment of Otorhinolaryngology, Head and Neck Surgery, and Audiology, Rigshospitalet, Copenhagen, Denmark.ORCID https://orcid.org/0000-0002-7806-7219
Valentyna YasinskaDepartment of Respiratory Medicine and Allergy, Karolinska University Hospital, Huddinge, Stockholm, Sweden.ORCID https://orcid.org/0000-0002-1379-1265
Tina SkjoldDepartment of Pulmonary Medicine, Allergy Center, Aarhus University Hospital, Aarhus, Denmark.
Jussi KarjalainenAllergy Centre, Tampere University Hospital, Tampere, Finland.
Apostolos BossiosDepartment of Respiratory Medicine and Allergy, Karolinska University Hospital, Huddinge, Stockholm, Sweden.ORCID https://orcid.org/0000-0002-0494-2690
Celeste PorsbjergRespiratory Research Unit, Department of Respiratory Medicine and Infectious Diseases, Bispebjerg Hospital, Copenhagen, Denmark.
Bispebjerg Hospital · DKQuantify Research (Sweden) · SETampere University · FIHaukeland University Hospital · NOKarolinska University Hospital · SEUniversity of Turku · FIAarhus University Hospital · DKFrederiksberg Hospital · DKHvidovre Hospital · DKKarolinska Institutet · SENovartis (Norway) · NORigshospitalet · DKTartu University Hospital · EEUmeå University · SEUniversity of Helsinki · FIUniversity of Iceland · ISUppsala University · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Real-life evidence on prevalence and management of severe asthma is limited. Nationwide population registries across the Nordic countries provide unique opportunities to describe prevalence and management patterns of severe asthma at population level. In nationwide register data from Sweden, Norway and Finland, we examined the prevalence of severe asthma and the proportion of severe asthma patients being managed in specialist care. Methods: This is a cross-sectional study based on the Nordic Dataset for Asthma Research (NORDSTAR) research collaboration platform. We identified patients with severe asthma in adults (aged ≥18 years) and in children (aged 6-17 years) in 2018 according to the European Respiratory Society/American Thoracic Society definition. Patients managed in specialist care were those with an asthma-related specialist outpatient contact (only available in Sweden and Finland). Results: Overall, we identified 598 242 patients with current asthma in Sweden, Norway and Finland in 2018. Among those, the prevalence of severe asthma was 3.5%, 5.4% and 5.2% in adults and 0.4%, 1.0%, and 0.3% in children in Sweden, Norway and Finland, respectively. In Sweden and Finland, 37% and 40% of adult patients with severe asthma and two or more exacerbations, respectively, were managed in specialist care; in children the numbers were 56% and 41%, respectively. Conclusion: In three Nordic countries, population-based nationwide data demonstrated similar prevalence of severe asthma. In children, severe asthma was a rare condition. Notably, a large proportion of patients with severe asthma were not managed by a respiratory specialist, suggesting the need for increased recognition of severe asthma in primary care.

Identifiers

PMID37020835
PMCPMC10068510
OpenAlexW4319728156

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.