Evidence map›Paper›PMID 37020118›Full record

ArticleBiochemical genetics2023

Association of Intelectin 1 Gene rs2274907 A > T Polymorphism with Obesity, Type 2 Diabetes, Serum Intelectin-1 Levels and Lipid Profiles in Turkish Adults.

Filiz Guclu-Geyik, Pınar Koseoglu, Gamze Guven, Gunay Can, Aysem Kaya, Neslihan Coban, Evrim Komurcu-Bayrak, Nihan Erginel-Unaltuna

Abstract read
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Article in Biochemical genetics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Filiz Guclu-GeyikDepartment of Genetics, Aziz Sancar Institute of Experimental Medicine, Istanbul University, Istanbul, Turkey. gfiliz@istanbul.edu.tr.ORCID http://orcid.org/0000-0003-4257-9930
Pınar KoseogluDepartment of Genetics, Aziz Sancar Institute of Experimental Medicine, Istanbul University, Istanbul, Turkey.ORCID http://orcid.org/0000-0003-4681-0968
Gamze GuvenDepartment of Genetics, Aziz Sancar Institute of Experimental Medicine, Istanbul University, Istanbul, Turkey.ORCID http://orcid.org/0000-0001-8576-5843
Gunay CanDepartment of Public Health, Cerrahpaşa Medical Faculty, Istanbul University-Cerrahpaşa, Istanbul, Turkey.ORCID http://orcid.org/0000-0001-5815-6700
Aysem KayaBiochemistry Laboratory, Institute of Cardiology, Istanbul University-Cerrahpaşa, Istanbul, Turkey.ORCID http://orcid.org/0000-0002-5716-1193
Neslihan CobanDepartment of Genetics, Aziz Sancar Institute of Experimental Medicine, Istanbul University, Istanbul, Turkey.ORCID http://orcid.org/0000-0002-6202-0408
Evrim Komurcu-BayrakDepartment of Genetics, Aziz Sancar Institute of Experimental Medicine, Istanbul University, Istanbul, Turkey.ORCID http://orcid.org/0000-0003-1271-1208
Nihan Erginel-UnaltunaDepartment of Genetics, Aziz Sancar Institute of Experimental Medicine, Istanbul University, Istanbul, Turkey.ORCID http://orcid.org/0000-0003-0562-0455
Istanbul University · TRIstanbul University-Cerrahpaşa · TRHUN-REN Institute of Experimental Medicine · HU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The anti-inflammatory adipokine intelectin-1, which is encoded by the ITLN1 gene, is hypothesized to be linked to the pathogenesis of type 2 diabetes (T2DM) and obesity. The purpose of this study was to examine the effect of the ITLN1 gene polymorphism rs2274907 on obesity and T2DM in Turkish adults. The impact of genotype on lipid profiles and serum intelectin levels in the obese and diabetes groups was also investigated. Randomly selected 2266 adults (mean age, 55.0 ± 11.7 years; 51.2% women) participating in the population-based Turkish adult risk factor study were cross-sectionally analyzed. The genotyping of rs2274907 A > T polymorphism was performed by using the hybridization probe based LightSNiP assay in real-time PCR. T2DM were defined using the criteria of the American Diabetes Association. Obesity was described as Body mass index ≥ 30 kg/m

Indexed as

Diabetes Mellitus, Type 2LectinsObesityAgedCross-Sectional StudiesCytokinesFemaleGene FrequencyGenotypeGPI-Linked ProteinsHumansLipidsMaleMiddle AgedMiddle Eastern PeopleRisk FactorsCytokinesGPI-Linked ProteinsITLN1 protein, humanLectinsLipidsITLN1ObesityTriglycerideType 2 diabetes

Identifiers

PMID37020118
OpenAlexW4362634461

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.