Evidence map›Paper›PMID 37020029›Full record

ArticleNature2023

Tracking chromatin state changes using nanoscale photo-proximity labelling.

Ciaran P Seath, Antony J Burton, Xuemeng Sun, Gihoon Lee, Ralph E Kleiner, David W C MacMillan, Tom W Muir

Open access · greenAbstract read
In one paragraph

Article in Nature, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers.

0numbers the graph read from it
0cells of the map it votes in
58citing papers in PubMed
14.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

58 citing papers in PubMed, 99 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. AbioRxiv : the preprint server for biology · 2026
    Article
  9. Review
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Review
  16. Article
  17. Review
  18. Article
  19. Article
  20. Mutant p53 binds RNA to drive mitochondrial dysfunction.bioRxiv : the preprint server for biology · 2025
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Ciaran P Seath *Merck Center for Catalysis at Princeton University, Princeton, NJ, USA.
Antony J Burton *Department of Chemistry, Princeton University, Princeton, NJ, USA.
Xuemeng SunDepartment of Chemistry, Princeton University, Princeton, NJ, USA.
Gihoon LeeDepartment of Chemistry, Princeton University, Princeton, NJ, USA.ORCID http://orcid.org/0000-0003-0783-9899
Ralph E KleinerDepartment of Chemistry, Princeton University, Princeton, NJ, USA.ORCID http://orcid.org/0000-0003-0508-9975
David W C MacMillanMerck Center for Catalysis at Princeton University, Princeton, NJ, USA. dmacmill@princeton.edu.ORCID http://orcid.org/0000-0001-6447-0587
Tom W MuirDepartment of Chemistry, Princeton University, Princeton, NJ, USA. muir@princeton.edu.ORCID http://orcid.org/0000-0001-9635-0344
Princeton University · USScripps Research Institute · US

Funding

Shared Resources Core 2: Quantitative Proteomics CoreP01CA196539 · NCI · ROCKEFELLER UNIVERSITY · PI MUIR, TOM · 2015 to 2024
$17.6M
Photoredox Catalysis Applications in Organometallics and Chemical BiologyR35GM134897 · NIGMS · PRINCETON UNIVERSITY · PI David W MacMillan · 2020 to 2026
$6.3M
Structure, Function and Applications of InteinsR37GM086868 · NIGMS · PRINCETON UNIVERSITY · PI MUIR, TOM · 2012 to 2021
$5.4M
Structure, Function and Applications of InteinsR01GM086868 · NIGMS · ROCKEFELLER UNIVERSITY · PI MUIR, TOM · 2008 to 2025
$4.4M
Synergistic Catalysis for Chemical SynthesisR01GM103558 · NIGMS · PRINCETON UNIVERSITY · PI MACMILLAN, DAVID W · 2012 to 2019
$2.7M
Chemical Approaches to Illuminate the Epitranscriptome (Administrative/Equipment Supplement)R01GM132189 · NIGMS · PRINCETON UNIVERSITY · PI KLEINER, RALPH ELLIOT · 2019 to 2023
$1.6M
NCI NIH HHS P01 CA196539NIGMS NIH HHS R01 GM086868NIGMS NIH HHS R01 GM103558NIGMS NIH HHS R01 GM132189NIGMS NIH HHS R35 GM134897NIGMS NIH HHS R37 GM086868
6 · The paper itself

Abstract

Interactions between biomolecules underlie all cellular processes and ultimately control cell fate. Perturbation of native interactions through mutation, changes in expression levels or external stimuli leads to altered cellular physiology and can result in either disease or therapeutic effects

Indexed as

Cell NucleusChromatinCross-Linking ReagentsEnergy TransferEpigenomicsHumansInteinsIridiumMethaneMutationNeoplasmsPhotosensitizing AgentsProtein BindingProtein Interaction MapscarbeneChromatinCross-Linking ReagentsIridiumMethanePhotosensitizing Agents

Identifiers

PMID37020029
PMCPMC10408239
OpenAlexW4362602997

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.