Evidence map›Paper›PMID 37020028›Full record

ArticleNature2023

Establishment and function of chromatin organization at replication origins.

Erika Chacin, Karl-Uwe Reusswig, Jessica Furtmeier, Priyanka Bansal, Leonhard A Karl, Boris Pfander, Tobias Straub, Philipp Korber, Christoph F Kurat

Open access · greenAbstract read
PubMed Publisher
In one paragraph

Article in Nature, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
6.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 45 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Chromatin architecture sets origin licensing capacity.bioRxiv : the preprint server for biology · 2026
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Rotational settings quantize nucleosome movement by chromatin regulators.bioRxiv : the preprint server for biology · 2025
    Article
  11. Article
  12. Article
  13. Review
  14. Review
  15. Compact Origins and Where to Find Them: ORC's Guide to Genome-Wide Licensing.BioEssays : news and reviews in molecular, cellular and developmental biology · 2025
    Review
  16. Review
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Erika ChacinBiomedical Center Munich (BMC), Division of Molecular Biology, Faculty of Medicine, Ludwig-Maximilians-Universität in Munich, Martinsried, Germany.ORCID http://orcid.org/0000-0001-5872-3744
Karl-Uwe ReusswigMax Planck Institute of Biochemistry, DNA Replication and Genome Integrity, Martinsried, Germany.ORCID http://orcid.org/0000-0003-2544-4145
Jessica FurtmeierBiomedical Center Munich (BMC), Division of Molecular Biology, Faculty of Medicine, Ludwig-Maximilians-Universität in Munich, Martinsried, Germany.
Priyanka BansalBiomedical Center Munich (BMC), Division of Molecular Biology, Faculty of Medicine, Ludwig-Maximilians-Universität in Munich, Martinsried, Germany.ORCID https://orcid.org/0000-0002-8276-5466
Leonhard A KarlMax Planck Institute of Biochemistry, DNA Replication and Genome Integrity, Martinsried, Germany.ORCID https://orcid.org/0000-0001-7036-0501
Boris PfanderMax Planck Institute of Biochemistry, DNA Replication and Genome Integrity, Martinsried, Germany.ORCID http://orcid.org/0000-0003-2180-5054
Tobias StraubCore Facility Bioinformatics, BMC, Faculty of Medicine, Ludwig-Maximilians-Universität in Munich, Martinsried, Germany.ORCID http://orcid.org/0000-0002-0547-0453
Philipp KorberBiomedical Center Munich (BMC), Division of Molecular Biology, Faculty of Medicine, Ludwig-Maximilians-Universität in Munich, Martinsried, Germany.ORCID https://orcid.org/0000-0001-7526-6549
Christoph F KuratBiomedical Center Munich (BMC), Division of Molecular Biology, Faculty of Medicine, Ludwig-Maximilians-Universität in Munich, Martinsried, Germany. Christoph.kurat@bmc.med.lmu.de.ORCID http://orcid.org/0000-0003-0962-3258
Ludwig-Maximilians-Universität München · DEDana-Farber Cancer Institute · USMax Planck Institute of Biochemistry · DEUniversity of Cologne · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The origin recognition complex (ORC) is essential for initiation of eukaryotic chromosome replication as it loads the replicative helicase-the minichromosome maintenance (MCM) complex-at replication origins

Indexed as

ChromatinOrigin Recognition ComplexReplication OriginSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsAdenosine TriphosphatasesDNA-Binding ProteinsDNA ReplicationNucleosomesTranscription FactorsAdenosine TriphosphatasesCHD1 protein, S cerevisiaeChromatinDNA-Binding ProteinsINO80 complex, S cerevisiaeISW1 protein, S cerevisiaeISWI proteinNucleosomesORC1 protein, S cerevisiaeOrigin Recognition ComplexSaccharomyces cerevisiae ProteinsTranscription Factors

Identifiers

PMID37020028
OpenAlexW4362608393

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.