ArticleEuropean respiratory review : an official journal of the European Respiratory Society2023
Managing respiratory muscle weakness during weaning from invasive ventilation.
Article in European respiratory review : an official journal of the European Respiratory Society, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 4 of them syntheses that pooled it.
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The trial behind it
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Who cites it
25 citing papers in PubMed, 4 syntheses or guidelines pooled it, 45 citations in OpenAlex.
- Predictive value of diaphragmatic ultrasound for weaning outcomes in mechanically ventilated patients with acute exacerbation of chronic obstructive pulmonary disease: a systematic review and meta-analysis.Critical care (London, England) · 2026Pooled it
- The effect of respiratory training on lung function in intensive care unit patients: a systematic review and meta-analysis.BMC pulmonary medicine · 2026Pooled it
- Inspiratory muscle training in weaning from prolonged mechanical ventilation: a systematic review and meta-analysis.Frontiers in medicine · 2025Pooled it
- Low-Medium and High-Intensity Inspiratory Muscle Training in Critically Ill Patients: A Systematic Review and Meta-Analysis.Medicina (Kaunas, Lithuania) · 2024Pooled it
- Low CT-Derived Thoracic Muscle Area and Composite Weaning Failure in Mechanically Ventilated ICU Patients with Pneumonia: An Exploratory Analysis by Age Group.Journal of clinical medicine · 2026Article
- Defining a diaphragm-focused and patient-acceptable inspiratory muscle training (IMT) load in difficult to wean, mechanically ventilated patients: a protocol for a prospective, mixed methods study.BMJ open respiratory research · 2026Article
- Association of pectoralis major muscle cross-sectional area and mean density on chest CT with mortality in elderly COVID-19 patients: sex and side differences.BMC pulmonary medicine · 2026Article
- Persistent inspiratory muscle weakness among extubated patients after prolonged intubation is frequent and can be predicted early by maximal inspiratory pressure measured 12 days after its initial diagnosis: a prospective observational study.Critical care (London, England) · 2025Observational
- Diaphragm Morphology and Function in Neurocritical Care Patients: Uncovering Key Correlations With Respiratory Muscle Strength Under Mechanical Ventilation.Physiotherapy research international : the journal for researchers and clinicians in physical therapy · 2025Observational
- Intensive care unit-acquired muscle atrophy and weakness in critical illness: a review of long-term recovery strategies.Acute and critical care · 2025Article
- Influence of clinical severity and ventilation time on the use of timed inspiratory effort (TIE) as a predictor of success in ventilatory weaning.Journal of thoracic disease · 2025Article
- Advancements in imaging techniques for monitoring the respiratory muscles.Critical care (London, England) · 2025Review
- The Impact of Post-Operative Phrenic Nerve Dysfunction on Lung Function Parameters and Long-Term Outcomes After Lung Transplantation.Transplant international : official journal of the European Society for Organ Transplantation · 2025Article
- Be-SNAP: the Belgian Sepsis National Action Plan.Frontiers in public health · 2025Article
- Nursing-based precision assessment of nutrition and muscle status without ultrasound: a prospective observational study in mechanically ventilated neurosurgical patients.Frontiers in medicine · 2025Article
- Case Report: Multifactorial weaning failure after lung transplantation in paraquat-induced pulmonary fibrosis: a case-based clinical review.Frontiers in medicine · 2025Article
- Weaning Failure in Elderly Patients: A Systematic Review and Meta-Analysis.Journal of clinical medicine · 2024Review
- Prolonged weaning from mechanical ventilation: who, what, when and how?Breathe (Sheffield, England) · 2024Review
- Paradoxical breathing during sleep is associated with increased sleep apnea and reduced ventilatory capacities in high-level spinal cord injury.Journal of sleep research · 2024Article
- Postoperative conditions of rehabilitative interest in lung transplantation: a systematic review.Journal of Yeungnam medical science · 2024Article
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Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Weaning is a critical stage of an intensive care unit (ICU) stay, in which the respiratory muscles play a major role. Weakness of the respiratory muscles, which is associated with significant morbidity in the ICU, is not limited to atrophy and subsequent dysfunction of the diaphragm; the extradiaphragmatic inspiratory and expiratory muscles also play important parts. In addition to the well-established deleterious effect of mechanical ventilation on the respiratory muscles, other risk factors such as sepsis may be involved. Weakness of the respiratory muscles can be suspected visually in a patient with paradoxical movement of the abdominal compartment. Measurement of maximal inspiratory pressure is the simplest way to assess respiratory muscle function, but it does not specifically take the diaphragm into account. A cut-off value of -30 cmH
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Registered trials
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