Evidence map›Paper›PMID 37019258›Full record

ArticleEnvironmental pollution (Barking, Essex : 1987)2023

Metabolic pathways altered by air pollutant exposure in association with lipid profiles in young adults.

Jiawen Liao, Jesse Goodrich, Douglas I Walker, Yan Lin, Fred Lurmann, Chenyu Qiu, Dean P Jones, Frank Gilliland, Lida Chazi, Zhanghua Chen

Open access · greenAbstract read
In one paragraph

Article in Environmental pollution (Barking, Essex : 1987), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
7.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Jiawen LiaoDepartment of Population and Public Health Sciences, Keck School of Medicine of the University of Southern California, Los Angeles, CA, United States.
Jesse GoodrichDepartment of Population and Public Health Sciences, Keck School of Medicine of the University of Southern California, Los Angeles, CA, United States.
Douglas I WalkerGangarosa Department of Environmental Health, Rollins School of Public Health, Emory University, Atlanta, GA, United States.
Yan LinDuke Global Health Institute, Duke University, Durham, NC, United States.
Fred LurmannSonoma Technology Inc., Petaluma, CA, United States.
Chenyu QiuDepartment of Population and Public Health Sciences, Keck School of Medicine of the University of Southern California, Los Angeles, CA, United States.
Dean P JonesDepartment of Biochemistry, Emory University School of Medicine, Atlanta, GA, United States.
Frank GillilandDepartment of Population and Public Health Sciences, Keck School of Medicine of the University of Southern California, Los Angeles, CA, United States.
Lida ChaziDepartment of Population and Public Health Sciences, Keck School of Medicine of the University of Southern California, Los Angeles, CA, United States.
Zhanghua ChenDepartment of Population and Public Health Sciences, Keck School of Medicine of the University of Southern California, Los Angeles, CA, United States. Electronic address: zhanghuc@usc.edu.
University of Southern California · USEmory University · USDuke University · USSonoma Technology (United States) · US

Funding

Translational Research Support CoreP30ES007048 · NIEHS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI ROB S MCCONNELL · 1996 to 2026
$46.4M
Southern California Children's Environmental Health Center (SC-CEHC)P01ES022845 · NIEHS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI MCCONNELL, ROB S · 2013 to 2018
$4.0M
Metabolomic Signatures Linking Air Pollution, Obesity and DiabetesR00ES027870 · NIEHS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI CHEN, ZHANGHUA · 2019 to 2021
$747k
Near-Roadway and Ambient Air Pollution Exposure and the Gut Microbiome: Implications for Obesity and Insulin Resistance in AdolescenceR00ES027853 · NIEHS · UNIVERSITY OF COLORADO · PI ALDERETE, TANYA LYNN · 2018 to 2020
$721k
NIEHS NIH HHS P01 ES022845NIEHS NIH HHS P30 ES007048NIEHS NIH HHS R00 ES027853NIEHS NIH HHS R00 ES027870
6 · The paper itself

Abstract

Mounting evidence suggests that air pollution influences lipid metabolism and dyslipidemia. However, the metabolic mechanisms linking air pollutant exposure and altered lipid metabolism is not established. In year 2014-2018, we conducted a cross-sectional study on 136 young adults in southern California, and assessed lipid profiles (triglycerides, total cholesterol, high-density lipoprotein (HDL)-cholesterol, low-density lipoprotein (LDL)-cholesterol, very-low-density lipoprotein (VLDL)-cholesterol), and untargeted serum metabolomics using liquid chromatography-high-resolution mass spectrometry, and one-month and one-year averaged exposures to NO

Indexed as

Air PollutantsAir PollutionCross-Sectional StudiesEnvironmental ExposureFatty Acids, NonesterifiedHumansMetabolic Networks and PathwaysNitrogen DioxideParticulate MatterYoung AdultAir PollutantsFatty Acids, NonesterifiedNitrogen DioxideParticulate MatterAir pollutionCardiometabolic healthLipolysisMetabolomicsPathway analysis

Identifiers

PMID37019258
PMCPMC10243191
OpenAlexW4362584206

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.