Evidence map›Paper›PMID 37018787›Full record

ArticleArquivos brasileiros de cardiologia2023

Feasibility of Left Ventricle Lead Implantation in Cardiac Resynchronization Therapy Guided by Gated SPECT and Ventricular Remodeling.

Erivelton Alessandro do Nascimento, Fernando de Amorim Fernandes, Pedro Augusto Carvalho Mira, Zhuo He, Weihua Zhou, Claudio Tinoco Mesquita

Open access · diamondAbstract read
In one paragraph

Article in Arquivos brasileiros de cardiologia, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Erivelton Alessandro do NascimentoUniversidade Federal Fluminense - Serviço de Cardiologia, Hospital Universitário Antônio Pedro e Pós-Graduação em Ciências Cardiovasculares, Niterói, RJ - Brasil.ORCID 0000-0001-8260-6572
Fernando de Amorim FernandesUniversidade Federal Fluminense - Departamento de Radiologia - Universidade Federal Fluminense e Pós-Graduação em Ciências Cardiovasculares, Niterói, RJ - Brasil.
Pedro Augusto Carvalho MiraUniversidade Federal Fluminense - Laboratório de Ciências do Exercício, Niterói, RJ - Brasil.ORCID 0000-0003-1511-2681
Zhuo HeDepartment of Applied Computing, Michigan Technological University, Houghton - MI - EUA.
Weihua ZhouDepartment of Applied Computing, Michigan Technological University, Houghton - MI - EUA.
Claudio Tinoco MesquitaUniversidade Federal Fluminense - Departamento de Radiologia - Universidade Federal Fluminense e Pós-Graduação em Ciências Cardiovasculares, Niterói, RJ - Brasil.ORCID 0000-0002-1466-9413
Universidade Federal Fluminense · BRMichigan Technological University · USInstituto Nacional de Cardiologia · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCardiac resynchronization therapy (CRT) may benefit patients with advanced heart failure (HF). Abnormal eccentricity index by gated SPECT is related to structural and functional alterations of the left ventricle (LV).

objectiveThe aim of this study is to evaluate the feasibility of LV lead implantation guided by phase analysis and its relationship to ventricular remodeling.

methodsEighteen patients with indication for CRT underwent myocardial scintigraphy for implant orientation, and eccentricity and ventricular shape parameters were evaluated. P < 0.05 was adopted as statistical significance.

resultsAt baseline, most patients were classified as NYHA 3 (n = 12). After CRT, 11 out of 18 patients were reclassified to a lower degree of functional limitation. In addition, patients' quality of life was improved post-CRT. Significant reductions were observed in QRS duration, PR interval, end-diastolic shape index, end-systolic shape index, stroke volume, and myocardial mass post-CRT. The CRT LV lead was positioned concordant, adjacent, and discordant in 11 (61.1%), 5 (27.8%), and 2 (11.1%) patients, respectively. End-systolic and end-diastolic eccentricity demonstrated reverse remodeling post-CRT.

conclusionsLV lead implantation in CRT guided by gated SPECT scintigraphy is feasible. The placement of the electrode concordant or adjacent to the last segment to contract was a determinant of reverse remodeling.

Indexed as

Cardiac Resynchronization TherapyHeart FailureFeasibility StudiesHeart VentriclesHumansQuality of LifeTomography, Emission-Computed, Single-PhotonTreatment OutcomeVentricular Remodeling

Identifiers

PMID37018787
PMCPMC10392842
OpenAlexW4328091008

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.