Evidence map›Paper›PMID 37018770›Full record

ArticleCadernos de saude publica2023

COVID-19 vaccination and case fatality rates: a case report in a Brazilian municipality.

Moacir Paludetto Junior, André S Olak, Hisrael Passarelli-Araujo, Aline M Susuki, Michael Aschner, Henrique Pott-Junior, Monica M B Paoliello, Mariana R Urbano

Abstract readCase Reports
In one paragraph

Article in Cadernos de saude publica, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Mortality and potential years of life lost due to COVID-19 among healthcare workers in Bahia, 2020-2022.Epidemiologia e servicos de saude : revista do Sistema Unico de Saude do Brasil · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Moacir Paludetto JuniorSecretaria Municipal de Saúde, Arapongas, Brasil.ORCID 0000-0002-3039-6611
André S OlakDepartamento de Arquitetura e Urbanismo, Universidade Estadual de Londrina, Londrina, Brasil.ORCID 0000-0002-9595-7467
Hisrael Passarelli-AraujoDepartamento de Demografia, Universidade Federal de Minas Gerais, Belo Horizonte, Brasil.ORCID 0000-0003-3534-8392
Aline M SusukiDepartamento de Arquitetura e Urbanismo, Universidade Estadual de Londrina, Londrina, Brasil.ORCID 0000-0002-3679-5007
Michael AschnerDepartment of Molecular Pharmacology, Albert Einstein College of Medicine, New York, U.S.A.ORCID 0000-0002-2619-1656
Henrique Pott-JuniorDepartamento de Medicina, Universidade Federal de São Carlos, São Carlos, Brasil.ORCID 0000-0003-3126-2946
Monica M B PaolielloDepartment of Molecular Pharmacology, Albert Einstein College of Medicine, New York, U.S.A.ORCID 0000-0002-1898-6133
Mariana R UrbanoDepartamento de Estatística, Universidade Estadual de Londrina, Londrina, Brasil.ORCID 0000-0002-5411-5554

Funding

Mechanisms of Manganese NeurotoxicityR01ES010563 · NIEHS · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI Michael Aschner, Aaron B Bowman · 2001 to 2026
$11.9M
NIEHS NIH HHS R01 ES010563
6 · The paper itself

Abstract

Vaccination campaigns played a crucial role in reducing the incidence of COVID-19. However, a scant number of studies evaluated the impact of vaccination on case fatality rates (CFRs), including in Brazil. Our study aimed to compare CFRs according to vaccination status among subjects living in Arapongas (Paraná State, Brazil), considering the age composition of the population. Several strategies adopted by the Arapongas City Hall to minimize the spread of the virus were also elaborated upon. We accessed the 2021 database of the Arapongas Municipal Health Department, in which a total of 16,437 confirmed cases and 425 deaths were reported. The CFR was calculated as the ratio between COVID-19 deaths and the number of confirmed cases. Differences in age composition between unvaccinated and fully vaccinated individuals were observed in our study. Considering that CFR is a crude indicator and is highly sensitive to the age composition of the population, we adopted the average age distribution of confirmed cases among the three vaccination statuses (unvaccinated, partially, and fully) as a standard age distribution. The age-standardized CFR for unvaccinated and fully vaccinated groups were 4.55% and 2.42%, respectively. Fully vaccinated individuals showed lower age-specific CFRs in all age groups above 60 years than unvaccinated populations. Our findings strengthen the role of vaccination as a critical measure for preventing deaths among infected people and is particularly important to the ongoing reassessment of public health interventions and policies.

Indexed as

COVID-19Age DistributionBrazilCOVID-19 VaccinesHumansMiddle AgedVaccinationCOVID-19 Vaccines

Identifiers

PMID37018770
PMCPMC10463226

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.