Evidence map›Paper›PMID 37018229›Full record

SynthesisPLoS neglected tropical diseases2023

Scorpion envenomation-associated myocarditis: A systematic review.

Reza Fereidooni, Saeedreza Shirzadi, Seyyed Hamidreza Ayatizadeh, Mabrouk Bahloul, Amirali Tavangar, Seyed Alireza Zomorodian, Amirhossein Roshanshad, Ali Ardekani

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in PLoS neglected tropical diseases, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
9.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. Article
  3. Protective effect ofToxicon: X · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
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  9. Article
  10. Myocardial Ischemia after Severe Scorpion Envenomation: A Narrative Review.The American journal of tropical medicine and hygiene · 2024
    Review
  11. Review
  12. Article
  13. Review
  14. Scorpion-Induced Acute Coronary Syndrome: A Stinging Complication.Journal of investigative medicine high impact case reports
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Reza FereidooniHealth Policy Research Center, Institute of Health, Shiraz University of Medical Sciences, Shiraz, Iran.
Saeedreza ShirzadiHealth Policy Research Center, Institute of Health, Shiraz University of Medical Sciences, Shiraz, Iran.
Seyyed Hamidreza AyatizadehStudent Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran.
Mabrouk BahloulDepartment of Intensive Care, Habib Bourguiba University Hospital. Faculté de medicine de Sfax. Sfax University. Sfax, Tunisia.
Amirali TavangarDigestive Health Institute, University of California, Irvine Medical Center, Orange, California, United States of America.
Seyed Alireza ZomorodianShiraz Nephro-Urology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Amirhossein RoshanshadSchool of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
Ali ArdekaniHealth Policy Research Center, Institute of Health, Shiraz University of Medical Sciences, Shiraz, Iran.ORCID 0000-0001-7154-8864
Shiraz University of Medical Sciences · IRUniversity of California, Irvine Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundScorpion envenomation is associated with several complications. One of the most serious complications is the cardiac involvement in the form of myocarditis that remains the main reason for mortalities associated with scorpion envenomation. The present review aims to elucidate clinical and paraclinical findings associated with scorpion-related myocarditis, and to explore different management strategies and subsequent outcomes.

methodsWe searched PubMed, Web of Science, Scopus, and Google Scholar for articles related to keywords of myocarditis associated with scorpion envenomation up to May 1, 2022. Each article was carefully reviewed by two independent researchers. In case of disagreement for inclusion, we sought a third researcher opinion.

resultsA total of 703 cases from 30 case reports and 34 case series were included in our review. Myocarditis associated with scorpion envenomation was usually reported in children presenting with cardiopulmonary symptoms including pulmonary edema (60.7%) and shock or hypotension (45.8%). The most common ECG findings are sinus tachycardia (82%) followed by ST-T changes (64.6%). The management typically included inotropes (especially dobutamine), prazosin, diuretics, nitroglycerine and digoxin, when indicated. Mechanical ventilation was required in 36.7% of the patients. Mortality in confirmed scorpion-related myocarditis cases is estimated at 7.3%. Almost all survived cases showed rapid recovery and improvement in the left ventricular function.

conclusionEven though myocarditis associated with scorpion envenomation is rare, it remains a serious and in some of cases a fatal consequence of scorpion sting. In case of relative presentations, particularly in envenomed children, diagnosis of myocarditis should be considered. Early screening using serial cardiac markers and echocardiography can guide the treatment. Prompt treatment that focuses on cardiogenic shock and pulmonary edema usually results in a favorable outcome.

Indexed as

MyocarditisPulmonary EdemaScorpion StingsAnimalsChildDobutamineHumansRespiration, ArtificialScorpionsDobutamine

Identifiers

PMID37018229
PMCPMC10075437
OpenAlexW4362601826

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.