Evidence map›Paper›PMID 37017827›Full record

ArticleEJNMMI research2023

Candidate 3-benzazepine-1-ol type GluN2B receptor radioligands (

Lisheng Cai, Jeih-San Liow, Cheryl L Morse, Sanjay Telu, Riley Davies, Lester S Manly, Sami S Zoghbi, Frederick T Chin, Robert B Innis, Victor W Pike

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in EJNMMI research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 79% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. A Study of 3-Substituted 7-Methoxy-2,3,4,5-tetrahydro-1Molecules (Basel, Switzerland) · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Lisheng CaiMolecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, 10 Center Dr, Bldg 10, Room B3 C346, Bethesda, MD, 20892, USA. LishengCai@mail.nih.gov.ORCID http://orcid.org/0000-0002-9680-8391
Jeih-San LiowMolecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, 10 Center Dr, Bldg 10, Room B3 C346, Bethesda, MD, 20892, USA.
Cheryl L MorseMolecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, 10 Center Dr, Bldg 10, Room B3 C346, Bethesda, MD, 20892, USA.
Sanjay TeluMolecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, 10 Center Dr, Bldg 10, Room B3 C346, Bethesda, MD, 20892, USA.
Riley DaviesMolecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, 10 Center Dr, Bldg 10, Room B3 C346, Bethesda, MD, 20892, USA.
Lester S ManlyMolecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, 10 Center Dr, Bldg 10, Room B3 C346, Bethesda, MD, 20892, USA.
Sami S ZoghbiMolecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, 10 Center Dr, Bldg 10, Room B3 C346, Bethesda, MD, 20892, USA.
Frederick T ChinMolecular Imaging Program at Stanford, Department of Radiology, Stanford University, 1201 Welch Road, Rm. PS049, Stanford, CA, 94305-584, USA.
Robert B InnisMolecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, 10 Center Dr, Bldg 10, Room B3 C346, Bethesda, MD, 20892, USA.
Victor W PikeMolecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, 10 Center Dr, Bldg 10, Room B3 C346, Bethesda, MD, 20892, USA.
National Institutes of Health · USStanford University · US

Funding

PET Radiopharmaceutical SciencesZIAMH002793 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI PIKE, VICTOR W · 2009 to 2025
$69.8M
NIMH NIH HHS N01 MH032004
6 · The paper itself

Abstract

introductionWe recently reported

methodsNR2B-Me was assayed for binding affinity and selectivity to GluN2B in vitro.

resultsNR2B-Me enantiomers showed high GluN2B affinity and selectivity in vitro.

conclusion

Indexed as

GluN2BNMDA receptorNR2B-MePETσ1 receptor

Identifiers

PMID37017827
PMCPMC10076467
OpenAlexW4362602235

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.