Evidence map›Paper›PMID 37017634›Full record

ArticleThe journal of spinal cord medicine2023

Impact of the cough stimulation system on the care burden and life quality of caregivers of tetraplegics.

Anthony F DiMarco, Robert T Geertman, Gregory A Nemunaitis, Krzysztof E Kowalski

Open access · greenAbstract read
In one paragraph

Article in The journal of spinal cord medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 93% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Anthony F DiMarcoDepartment of Physical Medicine and Rehabilitation, MetroHealth Medical Center, Case Western Reserve University, Cleveland, Ohio, USA.
Robert T GeertmanDepartment of Neurosurgery, MetroHealth Medical Center, Case Western Reserve University, Cleveland, Ohio, USA.
Gregory A NemunaitisDepartment of Physical Medicine and Rehabilitation, MetroHealth Medical Center, Case Western Reserve University, Cleveland, Ohio, USA.
Krzysztof E KowalskiDepartment of Physical Medicine and Rehabilitation, MetroHealth Medical Center, Case Western Reserve University, Cleveland, Ohio, USA.
MetroHealth Medical Center · USCase Western Reserve University · USCleveland Clinic · US

Funding

CTSA INFRASTRUCTURE FOR PEDIATRIC RESEARCHUL1RR024989 · NCRR · CASE WESTERN RESERVE UNIVERSITY · PI DAVIS, PAMELA B · 2007 to 2011
$53.7M
Clinical and Translational Science Collaborative of ClevelandUL1TR002548 · NCATS · CASE WESTERN RESERVE UNIVERSITY · PI MCCOMSEY, GRACE A · 2018 to 2022
$35.5M
Clinical and Translational Science Collaborative of Northern Ohio, Catalyzing Linkages to Equity in Health (CLE Health)UM1TR004528 · NCATS · CASE WESTERN RESERVE UNIVERSITY · PI GRACE A MCCOMSEY · 2023 to 2026
$32.1M
Zosuquidar trihydrochloride for acute myeloid leukemia &refractory anemiaM01RR000080 · NCRR · UNIVERSITY HOSPITALS OF CLEVELAND · PI DEARBORN, DORR GELLATLY · 1985 to 2007
$22.2M
Evaluation of Spinal Cord Stimulation Using Wire Leads to Restore an Effective CoU01NS083696 · NINDS · CASE WESTERN RESERVE UNIVERSITY · PI DIMARCO, ANTHONY F. · 2013 to 2018
$2.7M
Spinal Cord Stimulation to Restore Cough In HumansR01NS049516 · NINDS · CASE WESTERN RESERVE UNIVERSITY · PI DIMARCO, ANTHONY F. · 2004 to 2007
$1.4M
NCATS NIH HHS UL1 TR002548NCATS NIH HHS UM1 TR004528NCRR NIH HHS M01 RR000080NCRR NIH HHS UL1 RR024989NINDS NIH HHS R01 NS049516NINDS NIH HHS U01 NS083696
6 · The paper itself

Abstract

objectivesTo determine caregiver burden and quality of life of primary family caregivers of participants with cervical SCI before and after use of the cough stimulation system (CSS).

designProspective assessment at four timepoints via questionnaire responses.

settingOut-patient hospital, United States.

participants15 primary family caregivers of participants with cervical SCI completed questionnaires including a respiratory care burden index (

resultsSCI participants had significant clinical improvements in terms of restoration of an effective cough and ability to manage airway secretions with use of the CSS. Restoration of expiratory muscle function with use of the CSS also resulted in less caregivers (CG) stress, greater control of their participants' breathing problems, and improvement in quality of life. Results of the caregiver burden inventory demonstrated marked reductions in caregiver burden in development items, physical health and social relationship. Overall caregiver burden fell from 43.4 ± 13.8 pre-implant to 32.4 ± 7.9 (P = 0.06), 31.7 ± 10.5 (P = 0.05), and 26.5 ± 9.3 (P = 0.01) at the 6-month, 1-year and 2-year timepoints.

conclusionUse of the CSS by cervical SCI participants results in restoration of an effective cough with significant clinical benefits. While caregiver burden is very high in primary family caregivers, they derive marked improvement in caregiver burden and quality of life with implementation of this device.

Indexed as

Quality of LifeSpinal Cord InjuriesCaregiver BurdenCaregiversCoughHumansProspective StudiesCaregiver burdenCoughSpinal cord injurySpinal cord stimulation

Identifiers

PMID37017634
PMCPMC10446787
OpenAlexW4362601570

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.