Evidence map›Paper›PMID 37017427›Full record

ArticleACS nano2023

Multimodal Optothermal Manipulations along Various Surfaces.

Hongru Ding, Pavana Siddhartha Kollipara, Kan Yao, Yiran Chang, Daniel J Dickinson, Yuebing Zheng

Open access · greenAbstract read
In one paragraph

Article in ACS nano, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Hongru DingWalker Department of Mechanical Engineering, The University of Texas at Austin, Austin, Texas 78712, United States.ORCID 0000-0003-1579-6825
Pavana Siddhartha KolliparaWalker Department of Mechanical Engineering, The University of Texas at Austin, Austin, Texas 78712, United States.ORCID 0000-0003-0166-6720
Kan YaoWalker Department of Mechanical Engineering, The University of Texas at Austin, Austin, Texas 78712, United States.ORCID 0000-0002-9144-2618
Yiran ChangDepartment of Molecular Biosciences, The University of Texas at Austin, Austin, Texas 78712, United States.
Daniel J DickinsonDepartment of Molecular Biosciences, The University of Texas at Austin, Austin, Texas 78712, United States.
Yuebing ZhengWalker Department of Mechanical Engineering, The University of Texas at Austin, Austin, Texas 78712, United States.ORCID 0000-0002-9168-9477
Walker (United States) · USThe University of Texas at Austin · US

Funding

Understanding developmental control of cell polarity using single-cell in vivo biochemistryR01GM138443 · NIGMS · UNIVERSITY OF TEXAS AT AUSTIN · PI DICKINSON, DANIEL J · 2020 to 2025
$2.4M
Four-dimensional Adhesion Frequency Assay for Full Profiling of Receptor-ligand Interactions on CellsR01GM146962 · NIGMS · UNIVERSITY OF TEXAS AT AUSTIN · PI ZHENG, YUEBING · 2022 to 2025
$1.5M
Single-molecule enzymology of protein kinasesR21GM144817 · NIGMS · UNIVERSITY OF TEXAS AT AUSTIN · PI DICKINSON, DANIEL J · 2022 to 2023
$424k
NIGMS NIH HHS R01 GM138443NIGMS NIH HHS R01 GM146962NIGMS NIH HHS R21 GM144817
6 · The paper itself

Abstract

Optical tweezers have provided tremendous opportunities for fundamental studies and applications in the life sciences, chemistry, and physics by offering contact-free manipulation of small objects. However, it requires sophisticated real-time imaging and feedback systems for conventional optical tweezers to achieve controlled motion of micro/nanoparticles along textured surfaces, which are required for such applications as high-resolution near-field characterizations of cell membranes with nanoparticles as probes. In addition, most optical tweezers systems are limited to single manipulation modes, restricting their broader applications. Herein, we develop an optothermal platform that enables the multimodal manipulation of micro/nanoparticles along various surfaces. Specifically, we achieve the manipulation of micro/nanoparticles through the synergy between the optical and thermal forces, which arise due to the temperature gradient self-generated by the particles absorbing the light. With a simple control of the laser beam, we achieve five switchable working modes [i.e., tweezing, rotating, rolling (toward), rolling (away), and shooting] for the versatile manipulation of both synthesized particles and biological cells along various substrates. More interestingly, we realize the manipulation of micro/nanoparticles on rough surfaces of live worms and their embryos for localized control of biological functions. By enabling the three-dimensional control of micro/nano-objects along various surfaces, including topologically uneven biological tissues, our multimodal optothermal platform will become a powerful tool in life sciences, nanotechnology, and colloidal sciences.

Indexed as

micro/nanoparticlesmultimodal manipulationoptical heatingoptical manipulationsingle-cell manipulation

Identifiers

PMID37017427
PMCPMC10391738
OpenAlexW4362601310

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.