Evidence map›Paper›PMID 37016885›Full record

ArticleNeurospine2023

Facet Articular Irregularity Is the Most Relevant Risk Factor for Rapidly Progressive Degenerative Cervical Myelopathy.

Yasuhiro Takeshima, Ai Okamoto, Shohei Yokoyama, Fumihiko Nishimura, Ichiro Nakagawa, Young-Soo Park, Hiroyuki Nakase

Open access · diamondAbstract read
In one paragraph

Article in Neurospine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Prevalence and distribution of cervical facet joint degeneration in patients with cervical spondylotic myelopathy without/with instability and ossification of the posterior longitudinal ligament-a comparative study.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025
    Article
  3. Article
  4. Exploration of the correlation between facet joints cross-sectional area asymmetry and cervical disc herniation.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Yasuhiro TakeshimaDepartment of Neurosurgery, Nara Medical University School of Medicine, Kashihara, Japan.
Ai OkamotoDepartment of Neurosurgery, Nara Medical University School of Medicine, Kashihara, Japan.
Shohei YokoyamaDepartment of Neurosurgery, Nara Medical University School of Medicine, Kashihara, Japan.
Fumihiko NishimuraDepartment of Neurosurgery, Nara Medical University School of Medicine, Kashihara, Japan.
Ichiro NakagawaDepartment of Neurosurgery, Nara Medical University School of Medicine, Kashihara, Japan.
Young-Soo ParkDepartment of Neurosurgery, Nara Medical University School of Medicine, Kashihara, Japan.
Hiroyuki NakaseDepartment of Neurosurgery, Nara Medical University School of Medicine, Kashihara, Japan.
Nara Medical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveFacet articular irregularity is associated with rapidly progressive degenerative cervical myelopathy (DCM). However, its significance compared with other known risk factors remains unknown. Therefore, this retrospective study aimed to clarify the potential impact of facet articular irregularity as a risk factor for rapid DCM progression.

methodsThis study included 141 consecutive patients with DCM who underwent surgical treatment at our institution. Clinical variables and radiological findings related to DCM progression were collected. Imaging findings were analyzed at the segmental level of myelopathy in each case. The patients were divided into 2 groups based on the presence or absence of rapid DCM progression, and independent risk factors were determined using logistic regression analyses.

resultsOverall, 131 patients with a mean age of 63.9 ± 12.6 years were analyzed; 27 patients (20.6%) were classified into the rapid DCM progression group. The mean age was significantly higher in the rapid progression group than in the slow progression group (72.4 ± 9.6 vs. 61.7 ± 12.4, p < 0.001). According to univariate analysis, facet articular irregularity, dynamic segmental translation (≥ 1.6 mm), upper cervical spine involvement above C4-5, history of cerebrovascular events, preceding minor trauma, local lordotic angle (≥ 4.5°), diabetes, hypertension, ligamentum flavum hypertrophy, and age were independent risk factors. Additionally, multivariate analysis showed that facet articular irregularity was the highest risk factor for rapid DCM progression (p = 0.001).

conclusionFacet articular irregularity is the most clinically significant finding among the known risk factors in patients with rapid DCM progression.

Indexed as

ArticularCervical myelopathyDegenerativeFacet jointLogistic regressionRisk factor

Identifiers

PMID37016885
PMCPMC10080442
OpenAlexW4362475798

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.