Evidence map›Paper›PMID 37016714›Full record

ArticleIEEE International Workshop on Genomic Signal Processing and Statistics : [proceedings]. IEEE International Workshop on Genomic Signal Processing and Statistics2013

Integrative Analysis of Multi-modal Correlated Imaging-Genomics Data in Glioblastoma.

Rolando J Olivares, Arvind Rao, Jeffrey S Morris, Veerabhadran Baladandayuthapani

Open access · greenAbstract read
In one paragraph

Article in IEEE International Workshop on Genomic Signal Processing and Statistics : [proceedings]. IEEE International Workshop on Genomic Signal Processing and Statistics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 93% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Rolando J OlivaresDepartment of Statistics, Texas A&M University.
Arvind RaoDepartment of Bioinformatics and Computational Biology, UT M.D. Anderson Cancer Center.
Jeffrey S MorrisDepartment of Biostatistics, UT M.D. Anderson Cancer Center.
Veerabhadran BaladandayuthapaniDepartment of Biostatistics, UT M.D. Anderson Cancer Center.
The University of Texas MD Anderson Cancer Center · USTexas A&M University · US

Funding

Integrative methods for high-dimensional genomics dataR01CA160736 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI BALADANDAYUTHAPANI, VEERABHADRAN · 2011 to 2014
$1.4M
NCI NIH HHS R01 CA160736
6 · The paper itself

Abstract

We propose a method to integrate high-dimensional genomics datasets across multiple platforms with multiple imaging outcomes. This new statistical framework uses a hierarchical model to integrate biological relationships across platforms to identify genes that associate with multiple correlated imaging outcomes. Our two-stage hierarchical model uses the information shared across the platforms and thus increasing the predictive power to identify the relevant genes. We assess the performance of our proposed method through simulation and apply to data obtained from the Cancer Genome Atlas Glioblastoma Multiforme dataset. Our proposed method discovers multiple copy number and microRNA regulated genes that are related to patients' imaging outcomes in glioblastoma.

Indexed as

Bayesian Analysisgenomicsintegrative analysisLasso Penalizationmultiple outcomessensitivityspecificity

Identifiers

PMID37016714
PMCPMC10068897
OpenAlexW2020109865

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.