Evidence map›Paper›PMID 37016703›Full record

ArticleOpen medicine (Warsaw, Poland)2023

miR-30b-5p targeting GRIN2A inhibits hippocampal damage in epilepsy.

Hu Zheng, Liuyang Wu, Huisheng Yuan

Open access · goldAbstract read
In one paragraph

Article in Open medicine (Warsaw, Poland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Hu ZhengDepartment of Neurosurgery, Hubei Provincial Hospital of Integrated Chinese & Western Medicine, Wuhan 430015, Hubei, China.
Liuyang WuDepartment of Neurosurgery, Hubei Provincial Hospital of Integrated Chinese & Western Medicine, Wuhan 430015, Hubei, China.
Huisheng YuanDepartment of Neurosurgery, Hubei Provincial Hospital of Integrated Chinese & Western Medicine, No. 11 Lingjiaohu Road, Jianghan District, Wuhan 430015, Hubei, China.
Integrated Chinese Medicine (China) · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

GRIN2A is associated with epilepsy (EP); however, its regulatory mechanism involving upstream miRNA (miR-30b-5p) has been overlooked. In this study, we aimed to identify the regulatory mechanism of the miR-30b-5p/GRIN2A axis in EP. Hippocampal neurons isolated from mice were incubated in magnesium-free medium for 48 h to establish an

Indexed as

epilepsymiRNAproliferationtargeting

Identifiers

PMID37016703
PMCPMC10066871
OpenAlexW4361860964

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.