ArticlebioRxiv : the preprint server for biology2023
Development of a Synthetic Biosensor for Chemical Exchange MRI Utilizing
Adam J Fillion, Alexander R Bricco, Harvey D Lee, David Korenchan, Christian T Farrar, Assaf A Gilad
Open access · greenAbstract readPreprint
In one paragraphArticle in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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0citing papers in PubMed
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What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
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3 · Its place in the literatureWho cites it
0 citing papers in PubMed, 0 citations in OpenAlex.
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4 · The recordCorrections and comments
5 · Who and what moneyAuthors and funding
6 authors at 2 institutions in 1 country.
Adam J FillionDepartment of Chemical Engineering, Michigan State University, East Lansing, Michigan, USA.
Alexander R BriccoDepartment of Biomedical Engineering, Michigan State University, East Lansing, Michigan, USA.
Harvey D LeeDepartment of Biomedical Engineering, Michigan State University, East Lansing, Michigan, USA.
David KorenchanAthinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, MA, USA.
Christian T FarrarAthinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, MA, USA.
Assaf A GiladDepartment of Chemical Engineering, Michigan State University, East Lansing, Michigan, USA.
Michigan State University · USHarvard University · US
Funding
Training/Dissemination-Resource for Molecular Imaging Agents in Precision MedicineP41EB024495 · NIBIB · UT SOUTHWESTERN MEDICAL CENTER · PI MARTIN G POMPER · 2017 to 2026
$11.8MClinically Translatable MRI Reporter Genes and Imaging Methods with Ultra-High Specificity and SensitivityR01EB031008 · NIBIB · MASSACHUSETTS GENERAL HOSPITAL · PI CHRISTIAN T FARRAR · 2021 to 2026
$4.0MBioengineering a novel electromagnetic perspective gene as a tool for wireless control of excitable cellsR01NS098231 · NINDS · MICHIGAN STATE UNIVERSITY · PI GILAD, ASSAF A, PELLED, GALIT · 2017 to 2021
$2.6MEvolution and optimization of synthetic <READ/WRITE> function from and into cells using genetic programmingR01EB030565 · NIBIB · MICHIGAN STATE UNIVERSITY · PI BANZHAF, WOLFGANG, GILAD, ASSAF A · 2021 to 2024
$2.3MSemi-synthetic, magneto-photonic circuit for non-invasive control of cellular functionR01EB031936 · NIBIB · CENTRAL MICHIGAN UNIVERSITY · PI GILAD, ASSAF A, HOCHGESCHWENDER, UTE H · 2021 to 2021
$2.0MMolecular Imaging for Detection of Synthetic Biology Circuits, Oscillators and Toggle Switches in Regenerative MedicineR01NS104306 · NINDS · MICHIGAN STATE UNIVERSITY · PI GILAD, ASSAF A · 2018 to 2021
$1.3MNIBIB NIH HHS P41 EB024495NIBIB NIH HHS R01 EB030565NIBIB NIH HHS R01 EB031008NIBIB NIH HHS R01 EB031936NINDS NIH HHS R01 NS098231NINDS NIH HHS R01 NS104306
6 · The paper itselfAbstract
Chemical Exchange Saturation Transfer (CEST) magnetic resonance imaging (MRI) has been identified as a novel alternative to classical diagnostic imaging. Over the last several decades, many studies have been conducted to determine possible CEST agents, such as endogenously expressed compounds or proteins, that can be utilized to produce contrast with minimally invasive procedures and reduced or non-existent levels of toxicity. In recent years there has been an increased interest in the generation of genetically engineered CEST contrast agents, typically based on existing proteins with CEST contrast or modified to produce CEST contrast. We have developed an
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PMCPMC10071792
OpenAlexW4323666433
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