ArticleTrials2023
Unicompartmental knee arthroplasty vs. high tibial osteotomy for medial knee osteoarthritis (UNIKORN): a study protocol of a randomized controlled trial.
Article in Trials, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05442242 (Unicompartmental Knee Arthroplasty vs. High Tibial Osteotomy for Medial Knee Osteoarthritis), which is not on this map. Cited by 6 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Unicompartmental Knee Arthroplasty vs. High Tibial Osteotomy for Medial Knee Osteoarthritis (UNIKORN): a Study Protocol of a Randomized Controlled Trial
Who cites it
6 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.
- High tibial osteotomy versus unicompartmental knee arthroplasty for medial compartment knee osteoarthritis: a comprehensive meta-analysis with patient-specific stratification by age, BMI, and preoperative activity levels.BMC musculoskeletal disorders · 2026Pooled it
- Sensor-based digital health technologies to capture endpoints in recent clinical trials: a scoping review.NPJ digital medicine · 2026Article
- Clinical Outcomes and Complications of Total knee Arthroplasty Following Previous Opening vs. Closing-Wedge High Tibial Osteotomy: A Systematic Review.The archives of bone and joint surgery · 2026Review
- Clinical Outcomes Following Medial Opening Wedge High Tibial Osteotomy in Patients With Medial Compartment Grade 4 Chondromalacia.Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2025Article
- Opening wedge high tibial osteotomy yields comparable to superior outcomes to unicompartmental knee arthroplasty at 2 years of follow-up in patients suffering from Ahlbäck III knee osteoarthritis: A propensity score-matched analysis.Journal of experimental orthopaedics · 2024Article
- Age-stratified analysis of HTO and UKA clinical effects in cross-indicated anterior medial osteoarthritis.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMedial knee osteoarthritis (OA) is a common health problem resulting in knee pain and limiting patients' physical activity. After failed conservative treatment, unicompartmental knee arthroplasty (UKA) and high tibial osteotomy (HTO) are possible surgical treatment options for this condition. There is a paucity of high-quality evidence in the literature comparing objective and subjective outcomes of these procedures. Also, there is no common agreement on whether these procedures provide comparable results in late-stage medial knee OA patients.
methodsWe will perform a prospective randomized controlled trial comparing HTO and UKA in patients with late-stage medial knee OA. 100 patients with isolated medial knee OA (KL III-IV) are assigned to either UKA (n = 50) or HTO (n = 50) procedure in patients 45-65 years of age. Our primary outcome will be KOOS ETHICS AND DISSEMINATION: The institutional review board of the Helsinki and Uusimaa Hospital District has approved the protocol. We will disseminate the findings through peer-reviewed publications.
trial registrationClinicalTrials.gov/TooloH NCT05442242. Registered on 7/1/2022.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.