Evidence map›Paper›PMID 37016378›Full record

ArticleBMC psychiatry2023

Determinants of effective treatment coverage for posttraumatic stress disorder: findings from the World Mental Health Surveys.

Dan J Stein, Alan E Kazdin, Richard J Munthali, Irving Hwang, Meredith G Harris, Jordi Alonso, Laura Helena Andrade, Ronny Bruffaerts, Graça Cardoso, Stephanie Chardoul and 17 more

Open access · goldAbstract read
In one paragraph

Article in BMC psychiatry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
7.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 23 citations in OpenAlex.

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  13. Post-traumatic stress disorder: evolving conceptualization and evidence, and future research directions.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

27 authors at 20 institutions in 18 countries.

Dan J SteinDepartment of Psychiatry & Mental Health and South African Medical Council Research Unit on Risk and Resilience in Mental Disorders, University of Cape Town and Groote Schuur Hospital, Cape Town, South Africa. dan.stein@uct.ac.za.
Alan E KazdinDepartment of Psychology, Yale University, New Haven, CT, USA.
Richard J MunthaliDepartment of Psychiatry, University of British Columbia, Vancouver, British Columbia, Canada.
Irving HwangDepartment of Health Care Policy, Harvard Medical School, Boston, MA, USA.
Meredith G HarrisSchool of Public Health, The University of Queensland, Herston, Queensland, Australia.
Jordi AlonsoHealth Services Research Unit, IMIM-Hospital del Mar Medical Research Institute, CIBER en Epidemiología y Salud Pública (CIBERESP), Pompeu Fabra University (UPF), Barcelona, Spain.
Laura Helena AndradeNúcleo de Epidemiologia Psiquiátrica - LIM 23, Instituto de Psiquiatria Hospital das Clinicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil.
Ronny BruffaertsUniversitair Psychiatrisch Centrum - Katholieke Universiteit Leuven (UPC-KUL), Campus Gasthuisberg, Leuven, Belgium.
Graça CardosoLisbon Institute of Global Mental Health, Comprehensive Health Research Center (CHRC)/NOVA Medical School, NOVA University of Lisbon, Lisbon, Portugal.
Stephanie ChardoulInstitute for Social Research, University of Michigan, Ann Arbor, MI, USA.
Giovanni de GirolamoIRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli, Brescia, Italy.
Silvia FlorescuNational School of Public Health, Management and Professional Development, Bucharest, Romania.
Oye GurejeDepartment of Psychiatry, University College Hospital, Ibadan, Nigeria.
Josep Maria HaroParc Sanitari Sant Joan de Déu, CIBERSAM, Universitat de Barcelona, Sant Boi de Llobregat, Barcelona, Spain.
Aimee N KaramInstitute for Development, Research, Advocacy and Applied Care (IDRAAC), Beirut, Lebanon.
Elie G KaramInstitute for Development, Research, Advocacy and Applied Care (IDRAAC), Beirut, Lebanon.
Viviane Kovess-MasfetyEcole des Hautes Etudes en Santé Publique (EHESP), EA 4057, Paris Descartes University, Paris, France.
Sing LeeDepartment of Psychiatry, Chinese University of Hong Kong, Tai Po, Hong Kong.
Maria Elena Medina-MoraNational Institute of Psychiatry Ramón de la Fuente Muñiz, Mexico City, Mexico.
Fernando Navarro-MateuUDIF-SM, Subdirección General de Planificación, Innovación y Cronicidad, Servicio Murciano de Salud. IMIB-Arrixaca, CIBERESP-Murcia, Murcia, Spain.
José Posada-VillaColegio Mayor de Cundinamarca University, Faculty of Social Sciences, Bogota, Colombia.
Juan Carlos StagnaroDepartamento de Psiquiatría y Salud Mental, Facultad de Medicina, Universidad de Buenos Aires, Buenos Aires, Argentina.
Margreet Ten HaveTrimbos-Instituut, Netherlands Institute of Mental Health and Addiction, Utrecht, Netherlands.
Nancy A SampsonDepartment of Health Care Policy, Harvard Medical School, Boston, MA, USA.
Ronald C KesslerDepartment of Health Care Policy, Harvard Medical School, Boston, MA, USA.
Daniel V VigoDepartment of Psychiatry, University of British Columbia, Vancouver, British Columbia, Canada.
WHO World Mental Health Survey Collaborators
Harvard University · USSaint George Hospital · LBUniversity of British Columbia · CACentro San Giovanni di Dio Fatebenefratelli · ITChinese University of Hong Kong · HKÉcole des Hautes Études en Santé Publique · FRHospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo · BRInstitute for Development, Research, Advocacy and Applied Care · LBInstituto Nacional de Psiquiatría Ramón de la Fuente Muñiz · MXKU Leuven · BENational School of Public Health, Management and Professional Development · ROParc Sanitari Sant Joan de Déu · ESServicio Murciano de Salud · ESSouth African Medical Research Council · ZAThe University of Queensland · AUTrimbos Institute · NLUniversidad Colegio Mayor de Cundinamarca · COUniversidad de Buenos Aires · ARUniversitat Pompeu Fabra · ESUniversity College Hospital, Ibadan · NG

Funding

EPIDEMIOLOGY-- NATIONAL COMORBIDITY SURVEY REPLICATIONU01MH060220 · NIMH · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI KESSLER, RONALD C · 1999 to 2010
$18.7M
Risk Factors for Psychopathology in the WHO WMH SurveysR01MH070884 · NIMH · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI KESSLER, RONALD C · 2005 to 2009
$6.0M
Social Role Disability and Mental-Physical Co-MorbidityR01MH069864 · NIMH · KAISER FOUNDATION HEALTH PLAN OF WASHINGTON · PI VON KORFF, MICHAEL R · 2004 to 2007
$2.2M
CROSS-NATIONAL STUDIES OF DRUG INVOLVEMENT: WMH2000R01DA016558 · NIDA · MICHIGAN STATE UNIVERSITY · PI ANTHONY, JAMES CHRISTOPHER · 2003 to 2008
$1.7M
World Mental Health Consortium Annual Meeting 2003-07R13MH066849 · NIMH · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI HEERINGA, STEVEN G · 2003 to 2007
$735k
Lebanon-Epidemiology: The NCS Replication StudyR03TW006481 · FIC · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI KESSLER, RONALD C · 2004 to 2006
$142k
FIC NIH HHS R03 TW006481NIDA NIH HHS R01 DA016558NIMH NIH HHS R01 MH069864NIMH NIH HHS R01 MH070884NIMH NIH HHS R13 MH066849NIMH NIH HHS U01 MH060220
6 · The paper itself

Abstract

backgroundPosttraumatic stress disorder (PTSD) is associated with significant morbidity, but efficacious pharmacotherapy and psychotherapy are available. Data from the World Mental Health Surveys were used to investigate extent and predictors of treatment coverage for PTSD in high-income countries (HICs) as well as in low- and middle-income countries (LMICs).

methodsSeventeen surveys were conducted across 15 countries (9 HICs, 6 LMICs) by the World Health Organization (WHO) World Mental Health Surveys. Of 35,012 respondents, 914 met DSM-IV criteria for 12-month PTSD. Components of treatment coverage analyzed were: (a) any mental health service utilization; (b) adequate pharmacotherapy; (c) adequate psychotherapy; and (d) effective treatment coverage. Regression models investigated predictors of treatment coverage.

results12-month PTSD prevalence in trauma exposed individuals was 1.49 (S.E., 0.08). A total of 43.0% (S.E., 2.2) received any mental health services, with fewer receiving adequate pharmacotherapy (13.5%), adequate psychotherapy (17.2%), or effective treatment coverage (14.4%), and with all components of treatment coverage lower in LMICs than HICs. In a multivariable model having insurance (OR = 2.31, 95 CI 1.17, 4.57) and severity of symptoms (OR = .35, 95% CI 0.18, 0.70) were predictive of effective treatment coverage.

conclusionThere is a clear need to improve pharmacotherapy and psychotherapy coverage for PTSD, particularly in those with mild symptoms, and especially in LMICs. Universal health care insurance can be expected to increase effective treatment coverage and therefore improve outcomes.

Indexed as

Mental Health ServicesStress Disorders, Post-TraumaticHealth SurveysHumansPsychotherapySurveys and QuestionnairesContact coverageEffective treatment coverageInsurancePosttraumatic stress disorder

Identifiers

PMID37016378
PMCPMC10074702
OpenAlexW4362532766

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.