Evidence map›Paper›PMID 37016049›Full record

ArticleBrazilian journal of microbiology : [publication of the Brazilian Society for Microbiology]2023

Staphylococcus nasal colonization in three species of non-human primates.

Juliana Georg da Silva, Glenda Culuchi, Cristiane Pinheiro Pestana, Haroldo Cid da Silva Junior, Felipe Betoni Saraiva, Tatiana Kugelmeier, Daniel Rouede, Ana Cristina Araújo Pinto, Thalita Pissinati, Ana Paula D'Alincourt Assef and 3 more

Open access · bronzeAbstract read
In one paragraph

Article in Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology], 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Juliana Georg da SilvaInstituto de Tecnologia em Imunobiológicos-Bio-Manguinhos/Fiocruz, Avenida Brasil 4365, Pavilhão Rocha Lima, sala 412, Rio de Janeiro, RJ, CEP21040-900, Brazil.
Glenda CuluchiInstituto de Tecnologia em Imunobiológicos-Bio-Manguinhos/Fiocruz, Avenida Brasil 4365, Pavilhão Rocha Lima, sala 412, Rio de Janeiro, RJ, CEP21040-900, Brazil.
Cristiane Pinheiro PestanaInstituto de Tecnologia em Imunobiológicos-Bio-Manguinhos/Fiocruz, Avenida Brasil 4365, Pavilhão Rocha Lima, sala 412, Rio de Janeiro, RJ, CEP21040-900, Brazil.
Haroldo Cid da Silva JuniorInstituto de Tecnologia em Imunobiológicos-Bio-Manguinhos/Fiocruz, Avenida Brasil 4365, Pavilhão Rocha Lima, sala 412, Rio de Janeiro, RJ, CEP21040-900, Brazil.
Felipe Betoni SaraivaInstituto de Tecnologia em Imunobiológicos-Bio-Manguinhos/Fiocruz, Avenida Brasil 4365, Pavilhão Rocha Lima, sala 412, Rio de Janeiro, RJ, CEP21040-900, Brazil.
Tatiana KugelmeierLaboratório de Pesquisa em Infecção Hospitalar do Instituto Oswaldo Cruz (LAPIH/IOC/Fiocruz), Rio de Janeiro, Brazil.
Daniel RouedeLaboratório de Pesquisa em Infecção Hospitalar do Instituto Oswaldo Cruz (LAPIH/IOC/Fiocruz), Rio de Janeiro, Brazil.
Ana Cristina Araújo PintoLaboratório de Pesquisa em Infecção Hospitalar do Instituto Oswaldo Cruz (LAPIH/IOC/Fiocruz), Rio de Janeiro, Brazil.
Thalita PissinatiLaboratório de Pesquisa em Infecção Hospitalar do Instituto Oswaldo Cruz (LAPIH/IOC/Fiocruz), Rio de Janeiro, Brazil.
Ana Paula D'Alincourt AssefServiço de Criação de Primatas não Humanos do Instituto de Ciência e Tecnologia em Biomodelos (ICTB/Fiocruz), Rio de Janeiro, Brazil.
Claudio Marcos Rocha-de-SouzaServiço de Criação de Primatas não Humanos do Instituto de Ciência e Tecnologia em Biomodelos (ICTB/Fiocruz), Rio de Janeiro, Brazil.
Thamirys Rachel Tavares E OliveiraServiço de Criação de Primatas não Humanos do Instituto de Ciência e Tecnologia em Biomodelos (ICTB/Fiocruz), Rio de Janeiro, Brazil.
José Procópio M SennaInstituto de Tecnologia em Imunobiológicos-Bio-Manguinhos/Fiocruz, Avenida Brasil 4365, Pavilhão Rocha Lima, sala 412, Rio de Janeiro, RJ, CEP21040-900, Brazil. jprocopio@bio.fiocruz.br.ORCID http://orcid.org/0000-0002-0837-7414
Instituto de Tecnologia e Pesquisa · BRFundação Oswaldo Cruz · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bacterial nasal colonization is common in many mammals and Staphylococcus represents the main pathogen isolated. Staphylococcus nasal carriage in humans constitutes a risk factor for Staphylococcus infections pointing out the need for animal experimentation for nasal colonization studies, especially for vaccine development. A limitation in addressing this hypothesis has been a lack of appropriate animal model. Murine models do not mimic human nasal colonization studies. Non-human primates (NHP) remain the best classical models for nasal colonization studies. In this study, we analyzed nasal colonization between two species of Old World monkeys (cynomolgus and rhesus) and a New World monkey (squirrel monkey) from breeding colony at Fiocruz (Brazil). Sixty male and female NHP with the average age of 1-21 years old, comprising twenty animals of each species, were analyzed. Nine different Staphylococcus species (S. aureus, S. cohnii, S. saprophyticus, S. haemolyticus, S. xylosus, S. warneri, S. nepalensis, S. simiae, and S. kloosi) were identified by MALDI-TOF and 16S rRNA gene sequence analyses. Antibiotic resistance was not detected among the isolated bacterial population. S. aureus was the main isolate (19 strains), present in all species, predominant in cynomolgus monkeys (9/20) and squirrel monkeys (7/20). spa typing was used to examine the clonal structure and genetic profile of Staphylococcus aureus isolates. Eight (8) spa types were identified among the S. aureus strains. A major cluster was identified, corresponding to a new spa type t20455, and no spa types found in this study were seen before in Brazil.

Indexed as

Methicillin-Resistant Staphylococcus aureusStaphylococcal InfectionsAnimalsCarrier StateFemaleHumansMaleMammalsMiceNosePrimatesRNA, Ribosomal, 16SStaphylococcusStaphylococcus aureusRNA, Ribosomal, 16SAnimal modelNasal colonizationNon-human primatesStaphylococcus spp.

Identifiers

PMID37016049
PMCPMC10072810
OpenAlexW4362594874

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.